D
Duanman He
Publications - 3
Citations - 29
Duanman He is an academic researcher. The author has contributed to research in topics: T cell & Macrophage. The author has an hindex of 1, co-authored 3 publications receiving 4 citations.
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Journal ArticleDOI
Immunoglobulin-Like Transcript 5 Inhibits Macrophage-Mediated Bacterial Killing and Antigen Presentation During Sepsis.
Siqi Ming,Musheng Li,Minhao Wu,Jianhui Zhang,Haibo Zhong,Junyang Chen,Yaopan Huang,Jun Bai,Li Huang,Juan Chen,Quanshi Lin,Jiao Liu,Jianping Tao,Duanman He,Xi Huang +14 more
TL;DR: In vivo experiment demonstrated that pretreatment with ILT5 blocking peptide improved the survival and pulmonary pathology of septic mice, and identifiedILT5 as an immunosuppressive regulator during sepsis, which may provide potential therapeutic strategy for sepsi.
Journal ArticleDOI
TREM-2 promotes Th1 responses by interacting with the CD3ζ-ZAP70 complex following Mycobacterium tuberculosis infection
Yongjian Wu,Minhao Wu,Siqi Ming,Siqi Ming,Xiaoxia Zhan,Shengfeng Hu,Xingyu Li,Huan Yin,Can Cao,Jiao Liu,Jinai Li,Zhilong Wu,Jie Zhou,Lei Liu,Sitang Gong,Duanman He,Xi Huang +16 more
TL;DR: The role of TREM-2 in in vivo models of infection and inflammation remains controversial as discussed by the authors, however, it has been shown that TREM2 expression on CD4+ T cells was induced by Mycobacterium tuberculosis infection in both humans and mice and positively associated with T cell activation and an effector memory phenotype.
Journal ArticleDOI
TLT2 Suppresses Th1 Response by Promoting IL-6 Production in Monocyte Through JAK/STAT3 Signal Pathway in Tuberculosis.
Jinai Li,Can Cao,Yali Xiang,Zhongsi Hong,Duanman He,Haibo Zhong,Ye Liu,Yongjian Wu,Xiaobin Zheng,Huan Yin,Jie Zhou,Hanbin Xie,Xi Huang +12 more
TL;DR: It is demonstrated that TLT2 negatively regulates Th1 response against mycobacterial infection, which promotes IL-6 production through JAK/STAT3 signal pathway.