D
Dwaipayan Sen
Researcher at Heritage Institute of Technology
Publications - 77
Citations - 1475
Dwaipayan Sen is an academic researcher from Heritage Institute of Technology. The author has contributed to research in topics: Unfolded protein response & Chemistry. The author has an hindex of 18, co-authored 71 publications receiving 1086 citations. Previous affiliations of Dwaipayan Sen include Binghamton University & Christian Medical College & Hospital.
Papers
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Mesenchymal stem cells in cardiac regeneration: a detailed progress report of the last 6 years (2010-2015).
TL;DR: This in-depth review is an attempt to summarize the major sources of mesenchymal stem cells involved in myocardial regeneration, the significant mechanisms involved in the process with a focus on studies conducted in the last 6 years and the challenges that remain to be addressed.
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Spinal cord injury: pathophysiology, treatment strategies, associated challenges, and future implications.
TL;DR: The present review aims at providing an overview of the current treatment strategies and also gives an insight into the potential cell-based therapies for the treatment of SCI.
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MicroRNAs in Parkinson's disease.
Abhishek Singh,Dwaipayan Sen +1 more
TL;DR: The role played by microRNAs in regulating various genes responsible for the onset and pathogenesis of Parkinson’s disease is focused on and various literature evidences pointing at the usefulness of targeting specific micro RNAs as a potential alternate therapeutic strategy for successful impairment of the disease progression are discussed.
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Adeno-associated virus (AAV) vectors in gene therapy: immune challenges and strategies to circumvent them
Sangeetha Hareendran,Balaji Balakrishnan,Dwaipayan Sen,Sanjay Kumar,Alok Srivastava,Giridhara R. Jayandharan +5 more
TL;DR: The nature of the immune response documented against AAV in various pre‐clinical and clinical settings is summarised and the strategies to evade them are discussed.
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Bioengineering of AAV2 capsid at specific serine, threonine, or lysine residues improves its transduction efficiency in vitro and in vivo.
Nishanth Gabriel,Sangeetha Hareendran,Dwaipayan Sen,Rupali A. Gadkari,Govindarajan Sudha,Ruchita Selot,Mansoor Hussain,Ramya Dhaksnamoorthy,Rekha Samuel,Narayanaswamy Srinivasan,Alok Srivastava,Giridhara R. Jayandharan +11 more
TL;DR: The feasibility of the use of these novel AAV2 capsid mutant vectors in hepatic gene therapy is demonstrated by demonstrating the transduction efficiencies of 11 S/T→A and 7 K→R vectors were significantly higher than the A AV2-WT vectors.