E
E.C. Goulart
Publications - 4
Citations - 202
E.C. Goulart is an academic researcher. The author has contributed to research in topics: Glutathione reductase & Hepatoprotection. The author has an hindex of 4, co-authored 4 publications receiving 185 citations.
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Journal ArticleDOI
Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.
Manuella P. Kaster,Angelo O. Rosa,Matheus M. Rosso,E.C. Goulart,Adair R.S. Santos,Ana Lúcia S. Rodrigues +5 more
TL;DR: This is the first report of an antidepressant-like effect of adenosine in mice, apparently mediated through an interaction with A1 and A2A receptors.
Journal ArticleDOI
Antidepressant-like and antinociceptive-like actions of 4-(4′-chlorophenyl)-6-(4″-methylphenyl)-2-hydrazinepyrimidine Mannich base in mice
Ana Lúcia S. Rodrigues,Juliana M. Rosa,Vinicius M. Gadotti,E.C. Goulart,Manoel Mota dos Santos,A.V. Silva,B. Sehnem,L.S. Rosa,R.M. Gonçalves,R. Corrêa,Adair R.S. Santos +10 more
TL;DR: It is demonstrated that CPMPH had an antidepressant-like action that appears to be mediated through its interaction with serotonergic, dopaminergic and noradrenergic systems and the L-arginine-nitric oxide pathway.
Journal ArticleDOI
Protective effect of crude extract from Wedelia paludosa (Asteraceae) on the hepatotoxicity induced by paracetamol in mice.
Juliana M. Rosa,Patricia S. Brocardo,Daniela Balz,Ana Lúcia S. Rodrigues,Ana Paula Waltrick,Angelize Bagio,E.C. Goulart,Flavia Carla Meotti,Flavia Carla Meotti,Alcir Luiz Dafre,Adair R.S. Santos +10 more
TL;DR: W. paludosa protected against paracetamol‐induced hepatotoxicity, an effect not observed over oxidative stress‐related parameters, however, further studies will be required to explain the mechanisms involved in the hepatoprotection afforded by the crude extract.
Journal ArticleDOI
Effects of lead and/or zinc exposure during the second stage of rapid postnatal brain growth on delta-aminolevulinate dehydratase and negative geotaxis of suckling rats
TL;DR: The results indicate that lead and/or zinc treatment during the second stage of rapid postnatal brain growth affected ALA-D, but zinc was not sufficient to protect the enzyme from the effects of lead in brain, kidney and blood.