https://chemistry.mdma.ch/hiveboard/rhodium/pdf/archive/merbst/quinoline1999.pdf

Quinoline, quinazoline and acridone alkaloids

Natural phenanthrenes and their biological activity.

Bioassay-directed isolation of antifungal compounds from an ethyl acetate extract of Ruta graveolens leaves yielded two furanocoumarins, one quinoline alkaloid, and four quinolone alkaloids, including a novel compound, 1-methyl-2-[6‘-(3‘ ‘,4‘ ‘-methylenedioxyphenyl)hexyl]-4-quinolone The 1H and 13C NMR assignments of the new compound are reported Antifungal activities of the isolated compounds, together with 7-hydroxycoumarin, 4-hydroxycoumarin, and 7-methoxycoumarin, which are known to occur in Rutaceae species, were evaluated by bioautography and microbioassay Four of the alkaloids had moderate activity against Colletotrichum species, including a benomyl-resistant C acutatum These compounds and the furanocoumarins 5- and 8-methoxypsoralen had moderate activity against Fusarium oxysporum The novel quinolone alkaloid was highly active against Botrytis cinerea Phomopsis species were much more sensitive to most of the compounds, with P viticola being highly sensitive to all of the compounds Keyword

Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.

Chlorine-containing natural compounds in higher plants

Coumarins in the Rutaceae

Weitere phenanthrene aus dem rhizom von Tamus communis

Acridon-alkaloid-glukoside aus Ruta graveolens ☆

The co-occurrence of rutacridone and noracronycine in the roots of Boenninghausenia albiflora

Cumarine und chinolin-alkaloide aus der wurzelrinde von Ptelea trifoliata☆

A new coumarin-derivative has been isolated from the roots ofRuta graveolens. It could be identified by UV-, IR-, NMR- and mass-spectrometry as 3-(1′,1′-dimethylallyl)-6-(3′,3′-dimethylallyl)-umbelliferone, which was called gravelliferone. It represents a new type of 3-substituted coumarins.

E. Minker

Papers

Weitere phenanthrene aus dem rhizom von Tamus communis

Acridon-alkaloid-glukoside aus Ruta graveolens ☆

The co-occurrence of rutacridone and noracronycine in the roots of Boenninghausenia albiflora

Cumarine und chinolin-alkaloide aus der wurzelrinde von Ptelea trifoliata☆

[3-(3-1',1'-dimethylallyl)-6-(3',3'-dimethylallyl)-umbelliferone (gravelliferone) from the roots of Ruta graveolens].