E
Ealisha Jha
Researcher at Memorial University of Newfoundland
Publications - 28
Citations - 754
Ealisha Jha is an academic researcher from Memorial University of Newfoundland. The author has contributed to research in topics: Medicine & Biocompatibility. The author has an hindex of 13, co-authored 22 publications receiving 471 citations. Previous affiliations of Ealisha Jha include KIIT University.
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Journal ArticleDOI
Mechanistic insight to ROS and Apoptosis regulated cytotoxicity inferred by Green synthesized CuO nanoparticles from Calotropis gigantea to Embryonic Zebrafish.
Puja Kumari,Pritam Kumar Panda,Ealisha Jha,Khushboo Kumari,Kumari Nisha,M. Anwar Mallick,Suresh K. Verma +6 more
TL;DR: Cytotoxicity evaluation with Zebrafish revealed malfunctioned organ development with differential viability and hatching rate and valuable information of cytotoxic impact was demonstrated which can be influential in further studies of their eco-toxicological effects.
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Molecular aspects of core-shell intrinsic defect induced enhanced antibacterial activity of ZnO nanocrystals.
Suresh K. Verma,Ealisha Jha,Pritam Kumar Panda,Jugal Kishore Das,Arun Thirumurugan,Mrutyunjay Suar,S. K. S. Parashar +6 more
TL;DR: Synthesized nano ZnO exhibit size-dependent antibacterial action as consequences of interactions with cell membrane proteins via hydrogen bond interaction with amino acid residues followed by internalization, membrane depolarization and induction of reactive oxygen species generation.
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Altered physiochemical properties in industrially synthesized ZnO nanoparticles regulate oxidative stress; induce in vivo cytotoxicity in embryonic zebrafish by apoptosis
TL;DR: The mechanism of cytotoxicity in exposed embryonic Zebrafish as an effect of accumulation and internalization inside cells instigating to generation of hypoxic condition and interference with the normal adaptive stress regulation signaling pathways leading towards enhanced apoptosis is revealed.
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Mechanistic insight into the rapid one-step facile biofabrication of antibacterial silver nanoparticles from bacterial release and their biogenicity and concentration-dependent in vitro cytotoxicity to colon cells
Suresh K. Verma,Ealisha Jha,Babrubahan Sahoo,Pritam Kumar Panda,Arun Thirumurugan,S. K. S. Parashar,Mrutyunjay Suar +6 more
TL;DR: An in vitro assessment revealed their biogenicity and concentration-dependent cytotoxicity and genotoxicity in colon cell lines with the occurrence of morphological deformities, oxidative stress, apoptosis, and cell cycle arrest, providing an insight into the biogenic differences in the biological effects of silver nanoparticles.
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Rapid Novel Facile Biosynthesized Silver Nanoparticles From Bacterial Release Induce Biogenicity and Concentration Dependent In Vivo Cytotoxicity With Embryonic Zebrafish-A Mechanistic Insight.
Suresh K. Verma,Ealisha Jha,Pritam Kumar Panda,Anurag K. Mishra,Arun Thirumurugan,Biswadeep Das,S. K. S. Parashar,Mrutyunjay Suar +7 more
TL;DR: In vivo cytotoxicity with embryonic Zebrafish was found to be dependent on biogenicity and concentration of biosynthesized AgNPs as consequence of oxidative stress induction and apoptosis due to the influential regulation of sod1 and tp53 genes.