Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

Pattern Recognition and Machine Learning

An increase in world population along with a significant aging portion is forcing rapid rises in healthcare costs. The healthcare system is going through a transformation in which continuous monitoring of inhabitants is possible even without hospitalization. The advancement of sensing technologies, embedded systems, wireless communication technologies, nano technologies, and miniaturization makes it possible to develop smart systems to monitor activities of human beings continuously. Wearable sensors detect abnormal and/or unforeseen situations by monitoring physiological parameters along with other symptoms. Therefore, necessary help can be provided in times of dire need. This paper reviews the latest reported systems on activity monitoring of humans based on wearable sensors and issues to be addressed to tackle the challenges.

Wearable Sensors for Human Activity Monitoring: A Review

Advances in wireless technologies, low-power electronics, the internet of things, and in the domain of connected health are driving innovations in wearable medical devices at a tremendous pace. Wearable sensor systems composed of flexible and stretchable materials have the potential to better interface to the human skin, whereas silicon-based electronics are extremely efficient in sensor data processing and transmission. Therefore, flexible and stretchable sensors combined with low-power silicon-based electronics are a viable and efficient approach for medical monitoring. Flexible medical devices designed for monitoring human vital signs, such as body temperature, heart rate, respiration rate, blood pressure, pulse oxygenation, and blood glucose have applications in both fitness monitoring and medical diagnostics. As a review of the latest development in flexible and wearable human vitals sensors, the essential components required for vitals sensors are outlined and discussed here, including the reported sensor systems, sensing mechanisms, sensor fabrication, power, and data processing requirements.

Monitoring of Vital Signs with Flexible and Wearable Medical Devices

我的台灣, 看見心靈的故鄉 =2009林磐聳藝術與設計展

Life expectancy in most countries has been increasing continually over the several few decades thanks to significant improvements in medicine, public health, as well as personal and environmental hygiene. However, increased life expectancy combined with falling birth rates are expected to engender a large aging demographic in the near future that would impose significant burdens on the socio-economic structure of these countries. Therefore, it is essential to develop cost-effective, easy-to-use systems for the sake of elderly healthcare and well-being. Remote health monitoring, based on non-invasive and wearable sensors, actuators and modern communication and information technologies offers an efficient and cost-effective solution that allows the elderly to continue to live in their comfortable home environment instead of expensive healthcare facilities. These systems will also allow healthcare personnel to monitor important physiological signs of their patients in real time, assess health conditions and provide feedback from distant facilities. In this paper, we have presented and compared several low-cost and non-invasive health and activity monitoring systems that were reported in recent years. A survey on textile-based sensors that can potentially be used in wearable systems is also presented. Finally, compatibility of several communication technologies as well as future perspectives and research challenges in remote monitoring systems will be discussed.

Wearable Sensors for Remote Health Monitoring.

Ubiquitous vital signs sensing using wireless medical sensors are promising alternatives to conventional, in-hospital healthcare systems. In this work, a wearable ECG sensor is proposed. This sensor system combined an appropriate wireless protocol for data communication with capacitive ECG signal sensing and processing. The ANT protocol was used as a low-data-rate wireless module to reduce the power consumption and size of the sensor. Furthermore, capacitive ECG sensing is a simple technique that avoids direct contact with the skin and provides maximum convenience to the user. In our work, small capacitive electrodes were integrated into a cotton T-shirt together with a signal processing and transmitting board on a two-layer standard printed circuit board design technology. The entire system has small size, is thin, and has low power consumption compared to recent ECG monitoring systems. In addition, appropriate signal conditioning and processing were implemented to remove motion artifacts. The acquired ECG signals are comparable to ones obtained using conventional glued-on electrodes, and are easily read and interpreted by a cardiologist.

A wireless wearable ECG sensor for long-term applications

This paper introduces a human posture tracking platform to identify the human postures of sitting, standing or lying down, based on a smartwatch. This work develops such a system as a proof-of-concept study to investigate a smartwatch's ability to be used in future remote health monitoring systems and applications. This work validates the smartwatches' ability to track the posture of users accurately in a laboratory setting while reducing the sampling rate to potentially improve battery life, the first steps in verifying that such a system would work in future clinical settings. The algorithm developed classifies the transitions between three posture states of sitting, standing and lying down, by identifying these transition movements, as well as other movements that might be mistaken for these transitions. The system is trained and developed on a Samsung Galaxy Gear smartwatch, and the algorithm was validated through a leave-one-subject-out cross-validation of 20 subjects. The system can identify the appropriate transitions at only 10 Hz with an F-score of 0.930, indicating its ability to effectively replace smart phones, if needed.

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Can Smartwatches Replace Smartphones for Posture Tracking

Poor adherence to prescription medication can compromise treatment effectiveness and cost the billions of dollars in unnecessary health care expenses. Though various interventions have been proposed for estimating adherence rates, few have been shown to be effective. Digital systems are capable of estimating adherence without extensive user involvement and can potentially provide higher accuracy with lower user burden than manual methods. In this paper, we propose a smartwatch-based system for detecting adherence to prescription medication based the identification of several motions using the built-in tri-axial accelerometers and gyroscopes. The efficacy of the proposed technique is confirmed through a survey of medication ingestion habits and experimental results on movement classification.

A smartwatch-based medication adherence system

This paper presents a methodology for developing highly-accurate, continuous Arterial Blood Pressure (ABP) models using only Photoplethysmography (PPG). In contrast to prior approaches, we develop a system that exhibits dynamic temporal behavior which leads to increased accuracy in modeling ABP. We validate our approach using data from patients in the intensive care unit (ICU). We show that it is possible to build highly accurate, continuous blood pressure models using only finger pulse oximeters. Our methodology achieves accurate systolic blood pressure estimation with a root mean square error 2.58 ± 1.23 across the patient sample used. Furthermore, the continuous ABP signal is estimated with a root mean square error of 6.042 ± 3.26 and correlation coefficient of 0.95 ± 0.045. Our method enables designing robust Remote Health Monitoring Systems (RMS) for Heart Failure patients without requiring traditional blood pressure monitors.

Building Continuous Arterial Blood Pressure Prediction Models Using Recurrent Networks

The prevalence of ubiquitous computing enables new opportunities for lung health monitoring and assessment. In the past few years, there have been extensive studies on cough detection using passively sensed audio signals. However, the generalizability of a cough detection model when applied to external datasets, especially in real-world implementation, is questionable and not explored adequately. Beyond detecting coughs, researchers have looked into how cough sounds can be used in assessing lung health. However, due to the challenges in collecting both cough sounds and lung health condition ground truth, previous studies have been hindered by the limited datasets. In this paper, we propose Listen2Cough to address these gaps. We first build an end-to-end deep learning architecture using public cough sound datasets to detect coughs within raw audio recordings. We employ a pre-trained MobileNet and integrate a number of augmentation techniques to improve the generalizability of our model. Without additional fine-tuning, our model is able to achieve an F1 score of 0.948 when tested against a new clean dataset, and 0.884 on another in-the-wild noisy dataset, leading to an advantage of 5.8% and 8.4% on average over the best baseline model, respectively. Then, to mitigate the issue of limited lung health data, we propose to transform the cough detection task to lung health assessment tasks so that the rich cough data can be leveraged. Our hypothesis is that these tasks extract and utilize similar effective representation from cough sounds. We embed the cough detection model into a multi-instance learning framework with the attention mechanism and further tune the model for lung health assessment tasks. Our final model achieves an F1-score of 0.912 on healthy v.s. unhealthy, 0.870 on obstructive v.s. non-obstructive, and 0.813 on COPD v.s. asthma classification, outperforming the baseline by 10.7%, 6.3%, and 3.7%, respectively. Moreover, the weight value in the attention layer can be used to identify important coughs highly correlated with lung health, which can potentially provide interpretability for expert diagnosis in the future.

Ebrahim Nemati

Papers

A wireless wearable ECG sensor for long-term applications

Can Smartwatches Replace Smartphones for Posture Tracking

A smartwatch-based medication adherence system

Building Continuous Arterial Blood Pressure Prediction Models Using Recurrent Networks

Listen2Cough: Leveraging End-to-End Deep Learning Cough Detection Model to Enhance Lung Health Assessment Using Passively Sensed Audio