E
Edith Yamasaki
Researcher at University of California, Berkeley
Publications - 11
Citations - 14237
Edith Yamasaki is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Topoisomerase & Gene. The author has an hindex of 10, co-authored 11 publications receiving 14039 citations.
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Journal ArticleDOI
Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test
TL;DR: The methods described include the standard plate test, the use and storage of the bacterial tester strains, preparation and use of the liver homogenates, and the methods of inducing the rats for elevated microsomal enzyme activity.
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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals
TL;DR: There is a high correlation between carcinogenicity and mutagenicity: 90% (156/174) of carcinogens are mutagenic in the test and despite the severe limitations inherent in defining non-carcinogenicity, few "non-Carcinogens" show any degree of mutageniability.
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Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection
TL;DR: It is proposed that a ring system sufficiently planar for a stacking interaction with DNA base pairs and a part of the molecule capable of being metabolized to a reactive group are discussed in terms of the theory of frameshift mutagenesis.
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Concentration of mutagens from urine by absorption with the nonpolar resin XAD-2: cigarette smokers have mutagenic urine
Edith Yamasaki,Bruce N. Ames +1 more
TL;DR: It is shown that cigarette smokers have mutagenic urine while nonsmokers do not and this method is proposed to be used in monitoring the urine of human populations and of experimental animals in toxicological studies.
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Hair dyes are mutagenic: identification of a variety of mutagenic ingredients
TL;DR: It is shown here that 89% (150/169) of commercial oxidative-type (hydrogen peroxide) hair dye formulations are mutagenic in this test, a sensitive bacterial test for detecting carcinogens as mutagens.