E
Eduardo Rocha
Researcher at University of São Paulo
Publications - 397
Citations - 9595
Eduardo Rocha is an academic researcher from University of São Paulo. The author has contributed to research in topics: Brown trout & Trout. The author has an hindex of 46, co-authored 372 publications receiving 8133 citations. Previous affiliations of Eduardo Rocha include Marine Institute of Memorial University of Newfoundland & National Institutes of Health.
Papers
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Journal ArticleDOI
Identification of androgen, estrogen and progesterone receptor mRNAs in the eye.
TL;DR: The findings demonstrate that sex steroid receptor mRNAs exist in a variety of ocular tissues and suggest that these sites may represent target organs for androgens, estrogens and/or progestins.
Journal ArticleDOI
A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery.
Tais Gratieri,Guilherme M. Gelfuso,Eduardo Rocha,Victor Hugo Vitorino Sarmento,Osvaldo de Freitas,Renata Fonseca Vianna Lopez +5 more
TL;DR: The in situ forming gel comprised of poloxamer/chitosan is a promising tool for the topical treatment of ocular diseases and presents adequate mechanical and sensorial properties and remained in contact with the eye surface for a prolonged time.
Journal ArticleDOI
TFOS DEWS II Sex, Gender, and Hormones Report
David A. Sullivan,Eduardo Rocha,Pasquale Aragona,Janine A. Clayton,Juan Ding,Blanka Golebiowski,Ulrike Hampel,Alison M. McDermott,Debra A. Schaumberg,Debra A. Schaumberg,Sruthi Srinivasan,Piera Versura,Mark D. P. Willcox +12 more
TL;DR: Overall, sex, gender and hormones play a major role in the regulation of ocular surface and adnexal tissues, and in the difference in DED prevalence between women and men.
Journal ArticleDOI
Identification of androgen receptor protein and 5alpha-reductase mRNA in human ocular tissues.
Eduardo Rocha,L A Wickham,L A da Silveira,Kathleen L. Krenzer,F S Yu,Ikuko Toda,Benjamin Sullivan,David A. Sullivan +7 more
TL;DR: The findings show that androgen receptor protein exists in the human lacrimal gland, meibomian gland, cornea, bulbar and forniceal conjunctivae, lens epithelial cells, and retinal pigment epithel cells and demonstrate that the mRNAs for types 1 and 2 5α-reductase occur in theHuman ocular tissues may be target sites for androgen action.
Journal Article
Androgen influence on the meibomian gland.
David A. Sullivan,Benjamin Sullivan,M. David Ullman,Eduardo Rocha,Kathleen L. Krenzer,Kathleen L. Krenzer,Jennifer M. Cermak,Ikuko Toda,Marshall G. Doane,James E. Evans,L. Alexandra Wickham +10 more
TL;DR: The findings show that the meibomian gland is an androgen target organ and that androgens influence the lipid profile within this tissue, however, the extent to which androgens regulate the production of these lipids and whether this action may impact tear film stability remain to be determined.