Showing papers by "Edward J. Holland published in 1997"
TL;DR: In this paper, the authors evaluated the efficacy and risks of topical mitomycin C (MMC) for conjunctival-corneal intraepithelial neoplasia (CCIN).
169 citations
TL;DR: P prudent use of corticosteroids in selected patients with severe pain not responsive to analgesics or severe corneal or anterior chamber inflammation appears justified, and outcome after medical therapy between the groups was not significantly different.
Abstract: Purpose To clarify the role of topical corticosteroids in the management of Acanthamoeba keratitis. Methods The records of 38 patients diagnosed with Acanthamoeba keratitis at three institutions were retrospectively reviewed. Results After medical therapy alone, patients diagnosed within 1 month of symptom onset had an increased likelihood of being cured (p = 0.02) and attaining visual acuity of 20/60 or better (p Conclusions Topical corticosteroids were not associated with a higher rate of medical treatment failure in patients with Acanthamoeba keratitis. Rather, poor outcome was significantly related to diagnostic delays. Therefore prudent use of corticosteroids in selected patients with severe pain not responsive to analgesics or severe corneal or anterior chamber inflammation appears justified.
70 citations
TL;DR: In this paper, the authors performed a multicenter retrospective analysis of the indications and outcome in pediatric keratoplasty and found that a reasonable chance of success during the critical years of visual maturation and is associated with satisfactory visual results in one third to half the cases.
65 citations
TL;DR: Proper positioning of the haptics may be correlated with the development of fibrosis surrounding the haptic and therefore may be an important factor in the long-term stability of transsclerally sutured posterior chamber lenses.
23 citations
TL;DR: The results indicate that the accuracy in predicting the IOL implant power in PK/ TS-SPCL is quite comparable with that obtained for the Triple procedure, and the refractive results for each group are quite similar.
Abstract: PURPOSE: We determined how accurately we could predict the intraocular lens (IOL) power for a combined penetrating keratoplasty and transsclerally sutured posterior chamber lens implantation procedure (PK/TS-SPCL) compared with the Triple procedure (penetrating keratoplasty, extra-capsular cataract extraction, and IOL insertion). METHODS: We retrospectively evaluated the postoperative refractive results of 27 patients who had undergone PK/TS-SPCL and compared them with those of 46 patients who had undergone a Triple procedure. All patients with a final visual acuity > 20/50 who had surgery at the University of Minnesota between January 1988 and December 1993 were included in this study. RESULTS: The mean postoperative deviation from the predicted refractive error was 1.79 D for the Triple group and 1.81 D for the PK/TS-SPCL group (p = 0.95). Sixty-three percent of the Triple patients and 67% of the PK/TS-SPCL patients were within -2.00 D and +2.00 D of their predicted refractive error. As a group, the Triple patients had a mean postoperative keratometry reading of 44.64 compared with 45.58 for the PK/TS-SPCL patients (p = 0.12). CONCLUSION: These results indicate that our accuracy in predicting the IOL implant power in PK/ TS-SPCL is quite comparable with that obtained for the Triple procedure, and our refractive results for each group are quite similar.
6 citations