Eiji Okada

TL;DR: Near-infrared light propagation in various models of the adult head is analyzed by both time-of-flight measurements and mathematical prediction, and both the optical path length and the spatial sensitivity profile of the models with aCSF layer are quite different from those without the CSF layer.

TL;DR: Light propagation in adult head models is predicted by Monte Carlo simulation to investigate the effect of the superficial tissue thickness on the partial optical path length in the brain and on the spatial sensitivity profile and results indicate that it is not appropriate to use the mean optical length as an alternative to the partial Optical path length to compensate the NIRS signal for the difference in sensitivity caused by variation of the shallow tissue thickness.

TL;DR: Light propagation in the two-dimensional realistic adult and neonatal head models, whose geometries are generated from a magnetic resonance imaging scan of the human heads, is predicted by Monte Carlo simulation.

TL;DR: Light propagation in an adult head model with discrete scatterers distributed within theCSF layer has been predicted by Monte Carlo simulation to investigate the effect of the small amount of scattering caused by the arachnoid trabeculae in the CSF layer.

TL;DR: The results from the models show that at the typical optode spacings used in studies of the cerebral hemodynamic response to visual processing, an infrared spectroscopy measurement of intensity is sensitive to the outer 1-2 mm of the cortical gray matter.