E
Eileen A. McLaughlin
Researcher at University of Auckland
Publications - 183
Citations - 8139
Eileen A. McLaughlin is an academic researcher from University of Auckland. The author has contributed to research in topics: Sperm & Folliculogenesis. The author has an hindex of 48, co-authored 177 publications receiving 7111 citations. Previous affiliations of Eileen A. McLaughlin include Information Technology University & University of Newcastle.
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Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa.
TL;DR: The sperm mitochondria make a significant contribution to the oxidative stress experienced by defective human spermatozoa, as well as the subcellular origins of this activity are unclear.
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Awakening the oocyte: controlling primordial follicle development
TL;DR: Understanding the intracellular signalling systems that control oocyte maintenance and activation has significant implications for improving female reproductive productivity and longevity in mammals, and has application in domestic animal husbandry, feral animal population control and infertility in women.
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Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition.
TL;DR: A novel mechanism for mammalian gamete interaction is proposed whereby the activation of sperm-surface chaperones by tyrosine phosphorylation during capacitation may trigger conformational changes facilitating the formation of a functional zona pellucida receptor complex on the surface of mammalian spermatozoa.
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Kit ligand and c-Kit have diverse roles during mammalian oogenesis and folliculogenesis
TL;DR: Current understanding of the roles of KL and c-Kit within the mammalian ovary is detailed, with a particular focus on the functional diversity of this receptor-ligand interaction at different stages of oocyte and follicle development.
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Analysis of lipid peroxidation in human spermatozoa using BODIPY C11
TL;DR: BODIPY C(11) is an extremely useful probe for indexing peroxidative damage in human spermatozoa and was significantly correlated with the measurement of reactive oxygen species generation with dihydroethidium.