E
Eileen Goldstein
Publications - 3
Citations - 50
Eileen Goldstein is an academic researcher. The author has contributed to research in topics: Cell cycle checkpoint & NS3. The author has an hindex of 3, co-authored 3 publications receiving 49 citations.
Papers
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Journal ArticleDOI
R-253 disrupts microtubule networks in multiple tumor cell lines
Tarikere L. Gururaja,Dane Goff,Taisei Kinoshita,Eileen Goldstein,Stephanie Yung,John R. McLaughlin,Erlina Pali,Jianing Huang,Rajinder Singh,Sarkiz Daniel-Issakani,Yasumichi Hitoshi,Robin D. G. Cooper,Donald G. Payan +12 more
TL;DR: Both biochemical and cellular mechanistic studies indicate that R-253 could become a promising new tubulin-binding drug candidate for treating various malignancies.
Patent
Benzisothiazoles useful for treating or preventing HCV infection
Hui Hong,Eileen Goldstein,Emily Stauffer,Dane Goff,Rao Kolluri,Ihab S. Darwish,Rajinder Singh,Henry Lu +7 more
TL;DR: In this paper, the use of the benzisothiazoles and pharmaceutical compositions comprising the compounds to treat or prevent HCV infections was discussed, and the authors proposed a method to inhibit replication and/or proliferation of HCV virus.
Journal ArticleDOI
Discovery and Characterization of Substituted Diphenyl Heterocyclic Compounds as Potent and Selective Inhibitors of Hepatitis C Virus Replication
Peiyong Huang,Dane Goff,Qi Huang,Anthony Martinez,Xiang Xu,Scott Crowder,Sarkiz D. Issakani,Emily Anderson,Ning Sheng,Philip Achacoso,Ann Yen,Todd Kinsella,Ihab S. Darwish,Rao Kolluri,Hui Hong,Kunbin Qu,Emily Stauffer,Eileen Goldstein,Rajinder Singh,Donald G. Payan,H. Henry Lu +20 more
TL;DR: It is found that R803 was more effective than alpha interferon (IFN-α) at blocking HCV RNA replication in the replicon model, and could potentially be developed as a treatment for HCV infection.