E
Eivind Valen
Researcher at University of Bergen
Publications - 65
Citations - 13223
Eivind Valen is an academic researcher from University of Bergen. The author has contributed to research in topics: Ribosome profiling & Gene. The author has an hindex of 31, co-authored 62 publications receiving 11056 citations. Previous affiliations of Eivind Valen include Harvard University & University of Copenhagen.
Papers
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Journal ArticleDOI
Long-read single-molecule RNA structure sequencing using nanopore
Teshome Tilahun Bizuayehu,Kornel Labun,Martin Jakubec,Kirill Jefimov,Adnan M. Niazi,Eivind Valen +5 more
TL;DR: Single-Molecule Structure sequencing (SMS-seq) is presented that combines structural probing with native RNA sequencing to provide non-amplified, structural profiles of individual molecules with novel analysis methods and can capture tertiary interactions, dynamics of riboswitch ligand binding, and mRNA structural features.
Journal ArticleDOI
Small Open Reading Frames, How to Find Them and Determine Their Function
TL;DR: The abundance and potential function of many of these small open reading frames argues for the necessity of including sORFs in gene annotations and systematically characterizing these to understand their potential functional roles.
Book ChapterDOI
Transcript Isoform-Specific Estimation of Poly(A) Tail Length by Nanopore Sequencing of Native RNA.
TL;DR: In this article, the authors developed tailfindr, an R-based package for estimating poly(A) tail length from Oxford Nanopore sequencing data, from library preparation to downstream data analysis with tail findr.
Journal ArticleDOI
Deep conservation of ribosome stall sites across RNA processing genes.
TL;DR: In this paper, the authors used the deep conservation of protein synthesis machinery, hypothesizing that similar conservation could exist for functionally important locations of ribosome slowdown, here collectively called stall sites.
Posted ContentDOI
ORFik: a comprehensive R toolkit for the analysis of translation
TL;DR: ORFik as mentioned in this paper is a R/Bioconductor toolbox for studying translation and its regulation, which extends GenomicRanges from the genome to the transcriptome and implements a framework that integrates data from several sources.