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Ekaterina Kinnear
Researcher at Imperial College London
Publications - 12
Citations - 741
Ekaterina Kinnear is an academic researcher from Imperial College London. The author has contributed to research in topics: DNA vaccination & Cytotoxic T cell. The author has an hindex of 9, co-authored 12 publications receiving 483 citations.
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Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses
Annette B. Vogel,Laura Lambert,Ekaterina Kinnear,David C. Busse,Stephanie Erbar,Kerstin C. Reuter,Lena Wicke,Mario Perkovic,Tim Beissert,Heinrich Haas,Stephen T. Reece,Ugur Sahin,John S. Tregoning +12 more
TL;DR: In this paper, the authors compared synthetic mRNA and sa-RNA expressing influenza virus hemagglutinin, and concluded that saRNA is a promising platform for vaccines against viral diseases.
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Adjuvanted influenza vaccines
TL;DR: Improved understanding about the mechanisms of the immune response to vaccination and infection has led to advances in adjuvant technology and this review outlines the current use of adjuvants in human influenza vaccines, including what they are, why they are used and what is known of their mechanism of action.
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Airway T cells protect against RSV infection in the absence of antibody
Ekaterina Kinnear,Laura Lambert,Jacqueline U. McDonald,Hannah Cheeseman,Lisa J. Caproni,John S. Tregoning +5 more
TL;DR: A protective role for airway CD8 against RSV is demonstrated and the need for vaccines to induce antigen-specific airway cells is supported.
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Using Plasmids as DNA Vaccines for Infectious Diseases
TL;DR: This review will introduce some key concepts in the use of DNA plasmids as vaccines, including how the DNA enters the cell and is expressed, how it induces an immune response, and a summary of clinical trials with DNA vaccines.
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Mouse Models of Influenza Infection with Circulating Strains to Test Seasonal Vaccine Efficacy.
Helen T. Groves,Jacqueline U. McDonald,Pinky Langat,Ekaterina Kinnear,Paul Kellam,John W. McCauley,Joanna Ellis,Catherine Thompson,Ruth A. Elderfield,Lauren Parker,Wendy S. Barclay,John S. Tregoning +11 more
TL;DR: This observed reduction in protection suggests that mouse models of influenza virus vaccination and infection can be used as an additional tool to predict vaccine efficacy against drift strains.