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Elaine Yee Ling Cheng
Researcher at Hong Kong University of Science and Technology
Publications - 2
Citations - 182
Elaine Yee Ling Cheng is an academic researcher from Hong Kong University of Science and Technology. The author has contributed to research in topics: Genetically modified mouse & Hippocampal formation. The author has an hindex of 2, co-authored 2 publications receiving 150 citations.
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Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease
Amy K.Y. Fu,Kwok Wang Hung,Huiqian Huang,Shuo Gu,Yang Shen,Elaine Yee Ling Cheng,Fanny C.F. Ip,Xuhui Huang,Wing Yu Fu,Nancy Y. Ip +9 more
TL;DR: Blocking the EphA4-dependent pathway through knockdown studies or the use of small-molecule inhibitors effectively rescues the impaired synaptic transmission induced by Aβ and reverses impaired synaptic plasticity in AD mouse models, revealing a new disease-modifying therapeutic intervention for AD.
Journal ArticleDOI
Neuroprotective effect of a novel Chinese herbal decoction on cultured neurons and cerebral ischemic rats
Fanny Chui Fun Ip,Yu Ming Zhao,Yu Ming Zhao,Kim Wan Chan,Elaine Yee Ling Cheng,Estella P.S. Tong,Oormila Chandrashekar,Guang Miao Fu,Zhongzhen Zhao,Nancy Y. Ip +9 more
TL;DR: PSR is neuroprotective both in vitro and in vivo – it protects cultured neurons against NMDA excitotoxicity, and effectively reduces ischemic injury and neurobehavioral deficit in MCAO rats in both the pre- and post-treatment regimens.