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Elena R. Lozovskaya

Researcher at Harvard University

Publications -  25
Citations -  1768

Elena R. Lozovskaya is an academic researcher from Harvard University. The author has contributed to research in topics: Drosophila virilis & Genome. The author has an hindex of 21, co-authored 25 publications receiving 1730 citations. Previous affiliations of Elena R. Lozovskaya include Washington University in St. Louis.

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High intrinsic rate of DNA loss in Drosophila

TL;DR: Phylogenetic analysis of a non-LTR element, Helena, demonstrates that copies lose DNA at an unusually high rate, suggesting that lack of pseudogenes in Drosophila is the product of rampant deletion of DNA in unconstrained regions, and has important implications for the study of genome evolution in general and the 'C-value paradox' in particular.
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Modern thoughts on an ancyent marinere: function, evolution, regulation.

TL;DR: Two mechanisms that may be operative in mariner regulation are identified, one mechanism is overproduction inhibition, in which excessive wild-type transposase reduces the rate of excision of a target element, and a second mechanism is dominant-negative complementation, inwhich certain mutant transpos enzyme proteins antagonize the activity of the wild- type transposable elements.
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Diverse transposable elements are mobilized in hybrid dysgenesis in Drosophila virilis.

TL;DR: A system of hybrid dysgenesis in Drosophila virilis in which at least four unrelated transposable elements are all mobilized following a dysgenic cross is described, which is largely consistent with the superposition of at least three different systems of hybrid Dysgenesis.
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What restricts the activity of mariner-like transposable elements?

TL;DR: The issue of regulation is not only of theoretical importance in understanding the molecular and evolutionary genetics of MLEs, but also of practical significance in learning how best to use Mles in the germline transformation of insect pests and disease vectors.
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Molecular phylogeny and genome evolution in the Drosophila virilis species group: duplications of the alcohol dehydrogenase gene.

TL;DR: The developmental profile of Adh transcription suggests a distal/proximal promoter switch analogous to that in D. melanogaster, and the Adh genes in all species of the D. virilis group have among the lowest codon bias of any AdH genes so far reported in the genus Drosophila.