Elfar Adalsteinsson

TL;DR: Echo planar diffusion tensor imaging permits in vivo identification of the orientation and coherence of brain white matter tracts but suffers from field inhomogeneity‐induced geometric distortion.

TL;DR: The robustness, practicality, and demonstrated ability of predicting the change in iron deposition in adult aging suggest that regularized QSM algorithms using single-field-strength data are possible alternatives to tissue iron estimation requiring two field strengths.

TL;DR: In this article, the authors compared l1 and l2 norm regularized quantitative susceptibility mapping (QSM) algorithms to estimate the tissue magnetic susceptibility based on MRI signal phase and found that l1-regularized QSM is more sensitive in detecting age differences in brain stem structures as they revealed differences of much higher statistical significance between the young and elderly groups than did FDRI.

TL;DR: Degree of regional white matter coherence correlated with gait, balance, and interhemispheric transfer test scores, and age-related declines in intravoxel coherence was equally strong and strikingly similar in men and women.

TL;DR: A profile analysis of the integrity of white matter microstructure across the supratentorium and in selected focal regions using DTI data collected at high-field strength, with isotropic voxel acquisition and an analysis based on a concurrently-acquired field map to permit accurate quantification of artifact-prone, anterior and inferior brain regions.