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Elisabeth Bergen
Researcher at Medical University of Vienna
Publications - 37
Citations - 368
Elisabeth Bergen is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 7, co-authored 28 publications receiving 195 citations.
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Journal ArticleDOI
Activity of T-DM1 in Her2-positive breast cancer brain metastases.
Rupert Bartsch,Anna S. Berghoff,Ursula M. Vogl,Margaretha Rudas,Elisabeth Bergen,Peter Dubsky,Karin Dieckmann,Katja Pinker,Zsuzsanna Bago-Horvath,Arik Galid,Leopold Oehler,Christoph C. Zielinski,Michael Gnant,Guenther G. Steger,Matthias Preusser +14 more
TL;DR: T-DM1 apparently offers relevant clinical activity in BM and further investigation is warranted; still, lapatinib plus capecitabine is currently the best established systemic therapy option.
Journal ArticleDOI
Trastuzumab deruxtecan in HER2-positive breast cancer with brain metastases: a single-arm, phase 2 trial
Rupert Bartsch,Anna S. Berghoff,Julia Furtner,Maximilian Marhold,Elisabeth Bergen,Sophie Roider-Schur,Angelika M. Starzer,H. Forstner,B. Rottenmanner,Karin Dieckmann,Zsuzsanna Bago-Horvath,Helmuth Haslacher,Georg Widhalm,Aysegül Ilhan-Mutlu,Christoph Minichsdorfer,Thorsten Fuereder,Thomas Szekeres,Leopold Oehler,Birgit Gruenberger,Christian F. Singer,Ansgar Weltermann,Rainer Puhr,Matthias Preusser +22 more
TL;DR: The TUXEDO-1 trial as discussed by the authors showed that trastuzumab deruxtecan showed a high intracranial response rate in patients with active brain metastases from HER2-positive breast cancer and should be considered as a treatment option in this setting.
Journal ArticleDOI
Continued Endocrine Therapy Is Associated with Improved Survival in Patients with Breast Cancer Brain Metastases
Elisabeth Bergen,Anna S. Berghoff,Mela Medjedovic,Margaretha Rudas,Florian Fitzal,Zsuzsanna Bago-Horvath,Karin Dieckmann,Robert M. Mader,Ruth Exner,Michael Gnant,Christoph C. Zielinski,Guenther G. Steger,Matthias Preusser,Rupert Bartsch +13 more
TL;DR: Investigating the impact of ET after diagnosis of BM on outcome and clinical course of disease in patients with ER-positive MBC found continuing ET after BM diagnosis was associated with a significantly prolonged OS in this large single-center cohort.
Journal ArticleDOI
Current concepts and future directions in neoadjuvant chemotherapy of breast cancer.
TL;DR: Outcomes of selected studies investigating the addition of further chemotherapeutic drugs or biologically targeted agents to standard regimens are summarized and an overview of novel strategies currently under clinical evaluation is provided.
Journal ArticleDOI
Prognostic impact of breast cancer subtypes in elderly patients
Elisabeth Bergen,C. Tichy,Anna S. Berghoff,Margaretha Rudas,Peter Dubsky,Zsuzsanna Bago-Horvath,Robert M. Mader,Ruth Exner,Michael Gnant,Christoph C. Zielinski,Günther G. Steger,Matthias Preusser,Rupert Bartsch +12 more
TL;DR: In this paper, the impact of breast cancer subtypes on the clinical course of disease with special emphasis on the occurrence of brain metastases (BM) and outcome in an elderly BC population was analyzed.