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Showing papers by "Elisabetta Meucci published in 1987"

Journal Article•DOI•
Alkaline phosphatase inactivation by mixed function oxidation systems

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Alvaro Mordente1, Giacinto Abele Donato Miggiano1, Giuseppe Ettore Martorana1, Elisabetta Meucci1, Stefano Angelo Santini1, A Castelli1 •
Catholic University of the Sacred Heart1
01 Oct 1987-Archives of Biochemistry and Biophysics
TL;DR: Experiments with hydroxyl radical scavengers, enzyme substrates, products, and metal cofactors suggest that a "site-specific" radical attack takes place at or near the active center of alkaline phosphatase.

31 citations

Journal Article•
Vitamin C-bovine serum albumin binding behaviour

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Elisabetta Meucci, Giuseppe Ettore Martorana, A Ursitti, Giacinto Abele Donato Miggiano, Alvaro Mordente, A Castelli 
01 Mar 1987-Italian Journal of Biochemistry
TL;DR: Scatchard analysis indicates that the potency and the pattern of the binding can change gradually in the process of occupation of various sites because of albumin structural modifications.
Abstract: The binding of ascorbic acid and dehydroascorbic acid to bovine serum albumin is greatly heterogeneous. The Hill plots, as evaluated from the fluorescence quenching measurements, clearly show a biphasic behaviour. Scatchard analysis moreover indicates that the potency and the pattern of the binding can change gradually in the process of occupation of various sites because of albumin structural modifications.

5 citations