Elisabetta Straface

TL;DR: The presence of leptin receptor is demonstrated in human immature and mature DCs both at mRNA and protein level and its capacity to transduce leptin signaling leading to STAT-3 phosphorylation is demonstrated, demonstrating its ability to improve DC functions and to promote DC survival.

TL;DR: Current knowledge about the role of OS in the development of metabolic alterations characterizing MS is summarized, with particular regard to the occurrence of OS-correlated biomarkers, as well as to the use of therapeutic strategies based on natural antioxidants.

TL;DR: The results suggest that some biophenols, such as those contained in olive oil, may counteract the reactive oxygen metabolite-mediated cellular damage and related diseases, by improving in vivo antioxidant defenses.

TL;DR: Results indicate that peroxynitrite, a milestone of redox‐mediated damage in human pathology, can hijack human RBC toward senescence and apoptosis by a mechanism involving both cysteinyl and aspartyl proteases.

TL;DR: Exposure of K562 cells at 2.5 mT for periods to 96 hours induced significant changes in cell-surface structure and physiology without modification of proliferative capability as indicated by quantitative analysis.