Elisabetta Vecchi

TL;DR: In this paper, the stereochemistry and relative rates of Grignard reactions on some 4R-substituted cyclohexanones (R=tBu, Me, OMe. CO2Me, OCOPh and Cl) have been determined under two separate reaction conditions (MeMgI in C6H6 and MeMgCl in THF).

TL;DR: The stereochemistry of addition reactions of 4-t-Bu, 4-OMe and 4-C1 cyclohexanones, determined under seven different reaction conditions is described in this paper.

TL;DR: Methyl 4-methyl-5-oxo-hexanoate (4) and methyl 4methyl-6-phenyl-2H-pyran-2-one (6+7) were measured for reactions performed in benzene, diethyl ether, and tetrahydrofuran (with XCI).

TL;DR: In this paper, the 1H and 13C NMR chemical shift assignments of 10 −substituted decal 2 −ones, cis (H, CH3 and CO2CH3) and trans (COSY and HETCOR experiments, supported by selective spin decoupling experiments) were derived based on 2D COSY, HetCOR, and 2D CH3 experiments, and the discrimination between the cis and the trans conformations was ruled out on the basis of the J(1a,9) magnitudes related to dihedral angles

TL;DR: In this paper, the relative rates k ax and k eq of reduction reactions on title compounds have been measured under five different reaction conditions (NaBH 4 in i-PrOH, LiAlH 4 and NaAl H 4 in THF and LiAl 4 in E 2 O) and showed that axial substituents behave as far less electronegative than their equatorial counterpart.