E
Elizabeth Rue
Researcher at Johns Hopkins University
Publications - 3
Citations - 5766
Elizabeth Rue is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 3, co-authored 3 publications receiving 5402 citations.
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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
TL;DR: Hypoxia-inducible factor 1 (HIF-1) is found in mammalian cells cultured under reduced O2 tension and is necessary for transcriptional activation mediated by the erythropoietin gene enhancer in hypoxic cells.
Journal ArticleDOI
Characterization and localization of Mox2, the gene encoding the murine homolog of the rat MRC OX-2 membrane glycoprotein
TL;DR: The genomic organization for the gene encoding the murine homolog of MRC OX-2 (Mox2) is reported, demonstrating that in addition to the canonical transcript, this gene gives rise to an additional nonproductive transcript resulting from the absence of exon 2, which leads to a frameshift and premature translation termination.