E
Emily Clayton
Researcher at Lancaster University
Publications - 5
Citations - 119
Emily Clayton is an academic researcher from Lancaster University. The author has contributed to research in topics: Coronavirus & Loop-mediated isothermal amplification. The author has an hindex of 2, co-authored 4 publications receiving 38 citations.
Papers
More filters
Journal ArticleDOI
Structural and functional insights into non-structural proteins of coronaviruses.
TL;DR: In spite of the significant progress in studying coronaviruses structural and functional properties, there is an urgent need to understand the coronavirus evolutionary success that will be helpful to develop enhanced control strategies.
Journal ArticleDOI
Artificial Intelligence-Assisted Loop Mediated Isothermal Amplification (AI-LAMP) for Rapid Detection of SARS-CoV-2
Mohammed A. Rohaim,Emily Clayton,Irem Sahin,Julianne Vilela,Manar E. Khalifa,Mohammad Q. Al-Natour,Mahmoud Bayoumi,Aurore C. Poirier,Manoharanehru Branavan,Mukunthan Tharmakulasingam,Nouman S. Chaudhry,Ravinder Sodi,Amy Brown,Peter Burkhart,Wendy Hacking,Judy Botham,Joe Boyce,Hayley Wilkinson,Craig Williams,Jayde Whittingham-Dowd,Elisabeth Shaw,Matthew D. Hodges,Lisa Butler,Michelle D Bates,Roberto M. La Ragione,Wamadeva Balachandran,Anil Fernando,Muhammad Munir +27 more
TL;DR: This advanced AI algorithm-implemented LAMP (ai-LAMP) assay, targeting the RNA-dependent RNA polymerase gene, showed high analytical sensitivity and specificity for SARS-CoV-2 and was shown to be reliable, highly specific and significantly more sensitive than the current gold standard qRT-PCR.
Journal ArticleDOI
Fundamental Characteristics of Bat Interferon Systems.
Emily Clayton,Muhammad Munir +1 more
TL;DR: This review aims to explore the bat IFN system and developments in its diverse IFN features, focusing mainly on the model species, the Australian black flying fox, while also highlighting bat innate immunity as an exciting and fruitful area of research to understand their ability to control viral-mediated pathogenesis.
Journal ArticleDOI
Structural Bases of Zoonotic and Zooanthroponotic Transmission of SARS-CoV-2
Emily Clayton,Jacob Ackerley,Marianne Aelmans,Noor Shad Ali,Zoe Ashcroft,Clara Ashton,R. W. Barker,Vakare Budryte,Callum Burrows,Shanshan Cai,Alex Callaghan,Jake Carberry,Rebecca Chatwin,Isabella Davies,Chloe Farlow,Samuel Gamblin,Aida Iacobut,Adam Lambe,Francesca Lynch,Diana Mihalache,Amani Mokbel,Santosh Potamsetty,Zara Qadir,John M. Soden,Xiao Sun,Alexandru Vasile,O. R. Wheeler,Mohammed A. Rohaim,Muhammad Munir +28 more
TL;DR: This work structurally and genetically analysed the interaction between the spike protein, with a particular focus on receptor binding domains (RBDs), of SARS-CoV-2 and its receptor angiotensin-converting enzyme 2 (ACE2) for all conceivably susceptible groups of animals to gauge the structural bases of the Sars-Cov-2 host spectrum.
Posted ContentDOI
Artificial Intelligence-Assisted Loop Mediated Isothermal Amplification (ai-LAMP) for Rapid and Reliable Detection of SARS-CoV-2
Mohammed A. Rohaim,Emily Clayton,Irem Sahin,Julianne Vilela,Manar E. Khalifa,Mohammad Q. Al-Natour,Mahmoud Bayoumi,Aurore C. Poirier,Manoharanehru Branavan,Mukunthan Tharmakulasingam,Nouman S. Chaudhry,Ravinder Sodi,Amy Brown,Peter Burkhart,Wendy Hacking,Judy Botham,Joe Boyce,Hayley Wilkinson,Craig Williams,Michelle D Bates,Roberto M. La Ragione,Wamadeva Balachandran,Anil Fernando,Muhammad Munir +23 more
TL;DR: A de novo, high-resolution and comparative genomics guided reverse-transcribed loop-mediated isothermal amplification (LAMP) assay, targeting the RNA-dependent RNA polymerase gene, showed high analytical sensitivity and specificity for SARS-CoV-2.