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Enrique Chajon
Researcher at Institut Gustave Roussy
Publications - 53
Citations - 960
Enrique Chajon is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Radiation therapy & Cancer. The author has an hindex of 14, co-authored 52 publications receiving 679 citations.
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Journal ArticleDOI
Impact of head and neck cancer adaptive radiotherapy to spare the parotid glands and decrease the risk of xerostomia
Joël Castelli,Antoine Simon,Guillaume Louvel,O. Henry,Enrique Chajon,M. Nassef,Pascal Haigron,Guillaume Cazoulat,Juan David Ospina,Franck Jegoux,Karen Benezery,Renaud de Crevoisier +11 more
TL;DR: The purposes of the study were to estimate the PG overdose and the xerostomia risk increase during a “standard” IMRT (IMRTstd) and the benefits of an adaptive IMRT with weekly replanning to spare the PGs and limit the risk of xerOSTomia.
Journal ArticleDOI
Pretreatment 18F-FDG PET/CT Radiomics Predict Local Recurrence in Patients Treated with Stereotactic Body Radiotherapy for Early-Stage Non–Small Cell Lung Cancer: A Multicentric Study
Gurvan Dissaux,Dimitris Visvikis,R. Da-ano,Olivier Pradier,Enrique Chajon,Isabelle Barillot,L. Duvergé,Ingrid Masson,Ronan Abgral,Maria-Joao Ribeiro,Anne Devillers,Amandine Pallardy,Vincent Fleury,Marc-André Mahé,Renaud de Crevoisier,Mathieu Hatt,Ulrike Schick +16 more
TL;DR: 2 radiomic features derived from 18F-FDG PET were independently associated with local control in patients with non–small cell lung cancer undergoing SBRT and could be combined in an accurate predictive model, which could provide local relapse-related information and be helpful in clinical decision making.
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The synergistic effect of radiotherapy and immunotherapy: A promising but not simple partnership
TL;DR: The current concepts of the synergism between RT and immunotherapy, the molecular effects of RT in the tumor microenvironment, their impact on immune activation and its potential clinical applications in trials exploring this important therapeutic opportunity are summarized.
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Inverse Planning Approach for 3-D MRI-Based Pulse-Dose Rate Intracavitary Brachytherapy in Cervix Cancer
Enrique Chajon,Isabelle Dumas,Mahmoud Touleimat,Nicolas Magné,Jeremy Coulot,R. Verstraet,Dimitri Lefkopoulos,Christine Haie-Meder +7 more
TL;DR: The inverse planning simulated annealing (IPSA) software provided fast and automatic solutions for the optimization of dose distribution, however, the straightforward use of IPSA generated significant heterogeneity in dwell time values.
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Adaptive radiotherapy for head and neck cancer.
Joël Castelli,Joël Castelli,Antoine Simon,Antoine Simon,Caroline Lafond,Caroline Lafond,N. Perichon,B. Rigaud,B. Rigaud,Enrique Chajon,B. De Bari,Mahmut Ozsahin,Jean Bourhis,R. de Crevoisier,R. de Crevoisier +14 more
TL;DR: These studies suggest a benefit of ART in regard to decreasing xerostomia, increasing quality of life, and increasing local control for locally advanced HNC, and randomized trials are necessary before using the technique in routine practice.