Erica Secchettin

TL;DR: This pragmatic observational cohort study with an intention-to-treat design provides real-world evidence of outcomes associated with the most current primary chemotherapy regimens used for borderline resectable and locally advanced pancreatic ductal adenocarcinoma.

TL;DR: The development of postoperative infectious complications is a major determinant of outcome after pancreaticoduodenectomy and the reliable negative predictors of the outcome include preoperative biliary drain, site of infection, multidrug‐resistant bacteria infections and type of bacteria.

TL;DR: The present study aims to assess the impact of preoperative biliary drain on postoperative outcome and to define optimal serum bilirubin cut‐off to recommend biliary drainage in patients undergoing pancreatoduodenectomy.

TL;DR: Surveillance of the vast majority of presumed BD-IPMNs is safe, as the risk of PC is comparable to postoperative mortality of pancreatic surgery, and a growth rate ≥2.5 mm/yr is the main predictor of PC, reinforcing the role of repeated observations.

TL;DR: The weighted proportion of SGA of screening/surveillance programs published thus far is excellent, however, the probability of receiving surgery during the screening/Surveillance program is non-negligible, and unnecessary surgery is a potential negative outcome.