E
Erich F. Paulus
Researcher at University of Freiburg
Publications - 3
Citations - 410
Erich F. Paulus is an academic researcher from University of Freiburg. The author has contributed to research in topics: Translocase & Gluconeogenesis. The author has an hindex of 3, co-authored 3 publications receiving 381 citations.
Papers
More filters
Journal ArticleDOI
Chlorogenic acid and synthetic chlorogenic acid derivatives : Novel inhibitors of hepatic glucose-6-phosphate translocase
Horst Hemmerle,Burger Hans-Joerg,Peter Below,Gerrit Schubert,Robert Rippel,Schindler Peter,Erich F. Paulus,Andreas W. Herling +7 more
TL;DR: Functional assays on isolated perfused rat liver with compound 29i showed a dose-dependent inhibition of gluconeogenesis and glycogenolyosis, suggesting glucose-6-phosphatase as the locus of interference of the compound for inhibition of hepatic glucose production also in the isolated organ model.
Journal ArticleDOI
Chlorogenic Acid and Synthetic Chlorogenic Acid Derivatives: Novel Inhibitors of Hepatic Glucose-6-phosphate Translocase.
Horst Hemmerle,Burger Hans-Joerg,Peter Below,Gerrit Schubert,Robert Rippel,Schindler Peter,Erich F. Paulus,Andreas W. Herling +7 more
TL;DR: In this paper, chlorogenic acid was identified as a specific inhibitor of the glucose-6-phosphate translocase component of this enzyme system in microsomes of rat liver.
Journal ArticleDOI
Synthesis and Activity of Novel and Selective IKs-Channel Blockers
U. Gerlach,Joachim Brendel,Hans-Jochen Lang,Erich F. Paulus,Klaus Dr Weidmann,Andrea Brüggemann,Andreas Busch,Hartmut Suessbrich,Markus Bleich,Rainer Greger +9 more
TL;DR: It is found that the greatest influence on activity was found in the aromatic substituent and the sulfonamide group, and the most active compounds were alkoxy substituted.