Ernesto Falcoff

TL;DR: It is concluded that the combination of interferon gamma and pentavalent antimony is effective in treating seriously ill patients with refractory or previously untreated visceral leishmaniasis.

TL;DR: Serum TNF alpha levels in VL patients are a good parameter to monitor in determining host response to therapy, and this effect was further potentiated by treatment with recombinant interferon-gamma.

TL;DR: The results suggest that B and T lymphocytes might collaborate in vivo in the protection against T. cruzi infections by the production of anti‐trypomastigote antibodies and IFN‐γ, respectively.

TL;DR: Although several types of metastases were monitored, only skin nodules consistently exhibited changes that were suggestive of a therapeutic effect of the treatment regimen: either a simple decrease in size of some nodules or central necrosis accompanied by an inflammatory reaction.

TL;DR: A selective degradation of tRNA in incubated extracts, and an interferon-dependent inactivation of t RNA Leu are shown and it is reported that a single purified tRNA Leu species from yeast is able to restore the translation of all the synthetic and natural mRNAs tested.