E
Esko A. Nikkilä
Researcher at University of Helsinki
Publications - 154
Citations - 10485
Esko A. Nikkilä is an academic researcher from University of Helsinki. The author has contributed to research in topics: Lipoprotein lipase & Cholesterol. The author has an hindex of 56, co-authored 154 publications receiving 10357 citations. Previous affiliations of Esko A. Nikkilä include Finnish Red Cross & University of Tampere.
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Journal ArticleDOI
Lipid Alterations and Decline in the Incidence of Coronary Heart Disease in the Helsinki Heart Study
Vesa Manninen,M. Olli Elo,M. Heikki Frick,Kauko Haapa,Olli P. Heinonen,Pertti Heinsalmi,Pekka Helo,Jussi K. Huttunen,Pertti Kaitaniemi,Pekka Koskinen,Hanna Mäenpää,Marjatta Mälkönen,Matti Mänttäri,Seppo Norola,Amos Pasternack,Jarmo Pikkarainen,Matti Romo,Tom Sjöblom,Esko A. Nikkilä +18 more
TL;DR: The results of this study suggest that both elevating HDL and lowering LDL cholesterol levels are effective in the primary prevention of CHD.
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Apolipoprotein E polymorphism in the Finnish population: gene frequencies and relation to lipoprotein concentrations.
TL;DR: The data suggest that the apoE gene locus may be one factor responsible for the high LDL cholesterol concentrations in the Finnish population.
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Evidence for the role of hepatic endothelial lipase in the metabolism of plasma high density lipoprotein2 in man
TL;DR: The hypothesis that the heparin-releasable hepatic endothelial lipase has a physiological role in the degradation and removal of circulating HDL2 is supported.
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Lipoprotein lipase activity in adipose tissue and skeletal muscle of runners: relation to serum lipoproteins.
TL;DR: It is concluded that endurance training is associated with an adaptive increase of LPL activity not only in skeletal muscle but also in adipose tissue, and the high HDL-cholesterol levels of physically well-trained people are probably accounted for by the increased LPLactivity and the concomitant rapid turnover or triglyceride-rich lipoproteins.
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An immunochemical method for the selective measurement of two triglyceride lipases in human postheparin plasma.
TL;DR: The optimal conditions for the determination of the two postheparin plasma triglyceride hydrolases were shown to be similar to those described for the purified enzymes, making the methods suitable for studies of patients with various hyperlipidemias.