P
Paavo K.J. Kinnunen
Researcher at Aalto University
Publications - 327
Citations - 15387
Paavo K.J. Kinnunen is an academic researcher from Aalto University. The author has contributed to research in topics: Liposome & Phospholipid. The author has an hindex of 63, co-authored 327 publications receiving 14680 citations. Previous affiliations of Paavo K.J. Kinnunen include University of Helsinki & Washington University in St. Louis.
Papers
More filters
Journal ArticleDOI
Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology
Thomas Kirkegaard,Anke G. Roth,Nikolaj H.T. Petersen,Ajay K. Mahalka,Ole Dines Olsen,Irina Moilanen,Alicja Zylicz,Jens Knudsen,Konrad Sandhoff,Christoph Arenz,Paavo K.J. Kinnunen,Jesper Nylandsted,Marja Jäättelä +12 more
TL;DR: In this article, heat shock protein 70 (Hsp70) is shown to stabilize lysosomes by binding to an endolysosomal anionic phospholipid bis(monoacylglycero)phosphate (BMP), an essential co-factor for acid sphingomyelin metabolism.
Journal ArticleDOI
Biophysical properties of lipids and dynamic membranes
TL;DR: Some recent reports that the physical properties of the membrane can help control the function of transmembrane proteins and the motor-dependent elongation of internal organelles, such as the endoplasmic reticulum are highlighted.
Journal ArticleDOI
Membranes: a meeting point for lipids, proteins and therapies
Pablo V. Escribá,José M. González-Ros,Félix M. Goñi,Paavo K.J. Kinnunen,László Vígh,Lissete Sánchez-Magraner,Asia M. Fernández,Xavier Busquets,Ibolya Horváth,Gwendolyn Barceló-Coblijn +9 more
TL;DR: The role of membrane microdomains and lipid mediators in the control of heat‐shock protein response and stress sensing and signalling and the membrane sensor theory are studied.
Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal
Thomas Kirkegaard,Anke G. Roth,Nikolaj H.T. Petersen,Ajay K. Mahalka,Ole Dines Olsen,Irina Moilanen,Alicja Zylicz,Jens Knudsen,Konrad Sandhoff,Christoph Arenz,Paavo K.J. Kinnunen,Jesper Nylandsted,Marja Jäättelä +12 more
TL;DR: It is shown that Hsp70 stabilizes lysosomes by binding to an endolysosomal anionic phospholipid bis(monoacylglycero)phosphate (BMP), an essential co-factor for lysOSomal sphingomyelin metabolism.
Journal ArticleDOI
An immunochemical method for the selective measurement of two triglyceride lipases in human postheparin plasma.
TL;DR: The optimal conditions for the determination of the two postheparin plasma triglyceride hydrolases were shown to be similar to those described for the purified enzymes, making the methods suitable for studies of patients with various hyperlipidemias.