E
Eswar Krishnan
Researcher at Stanford University
Publications - 113
Citations - 8280
Eswar Krishnan is an academic researcher from Stanford University. The author has contributed to research in topics: Population & Hyperuricemia. The author has an hindex of 50, co-authored 113 publications receiving 7419 citations. Previous affiliations of Eswar Krishnan include University of Cambridge & University of Pittsburgh.
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Journal ArticleDOI
Gout and the risk of acute myocardial infarction.
TL;DR: The independent risk relationship between hyperuricemia and acute MI is confirmed and gouty arthritis is associated with an excess risk of acute MI, and this is not explained by its well-known links with renal function, metabolic syndrome, diuretic use, and traditional cardiovascular risk factors.
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Serum uric acid and cardiovascular disease: Recent developments, and where do they leave us?
TL;DR: Trials of SUA-lowering therapy in hyperuricemic patients evaluating the effect on cardiovascular outcomes are justified in high-risk patients because the magnitude of excess risk attributable to high SUA is likely to be small in healthy individuals.
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Long-term cardiovascular mortality among middle-aged men with gout.
Eswar Krishnan,Eswar Krishnan,Kenneth H. Svendsen,James D. Neaton,Greg Grandits,Lewis H. Kuller +5 more
TL;DR: Among middle-aged men, a diagnosis of gout accompanied by an elevated uric acid level imparts significant independent CVD mortality risk; among men with and without gout, the association between hyperuricemia and CVD was weak and did not persist when analysis was limited to men with hyperURicemia without a diagnosis.
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Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
Guangjin Li,Mingcan Yu,Mingcan Yu,Won Woo Lee,Michael Tsang,Eswar Krishnan,Eswar Krishnan,Cornelia M. Weyand,Cornelia M. Weyand,Jörg J. Goronzy,Jörg J. Goronzy +10 more
TL;DR: DUSP6 is a potential intervention target for restoring T cell responses in the elderly, which may augment the effectiveness of vaccination.
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Hyperuricemia and Incidence of Hypertension Among Men Without Metabolic Syndrome
TL;DR: It is concluded that the hyperuricemia–hypertension risk relationship is present among normotensive middle-aged men without diabetes/glucose intolerance or metabolic syndrome.