Etsuko Oshima

TL;DR: The results suggest that functional activity of the bilateral superior parietal lobules is closely related to performance time on the TMT-A, which might be a promising index of dysfunction of the superiorParietal area among mild AD patients.

TL;DR: It is shown that long-term administration of lithium at relatively low therapeutic concentrations to transgenic mice that recapitulate Alzheimer’s disease-like tau pathologies reduces tau lesions, primarily by promoting their ubiquitination rather than by inhibiting tau phosphorylation.

TL;DR: Investigation of the Japanese version of the revised Addenbrooke's Cognitive Examination (ACE-R J) for identifying mild cognitive impairment (MCI) and dementia proved to be an accurate cognitive instrument for detecting MCI and mild dementia.

TL;DR: A questionnaire evaluating person-centered care and QOL of elderly patients with dementia in both geriatric health service facilities (GHSF) and hospitals was used and found quite different patterns in the relationship of person- centered care scores to clinical characteristics.

TL;DR: The Japanese version of Addenbrooke's Cognitive Examination (ACE) is a very accurate instrument for the detection of early dementia, and should be widely used in clinical practice.