E
Evangelia Charmandari
Researcher at National and Kapodistrian University of Athens
Publications - 159
Citations - 7165
Evangelia Charmandari is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Glucocorticoid receptor & Glucocorticoid. The author has an hindex of 42, co-authored 142 publications receiving 6294 citations. Previous affiliations of Evangelia Charmandari include National Institutes of Health & Leeds General Infirmary.
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Endocrinology of the stress response.
TL;DR: The stress response is subserved by the stress system, which is located both in the central nervous system and the periphery, and the principal effectors include corticotropin-releasing hormone; arginine vasopressin; proopiomelanocortin-derived peptides alpha-melanocyte-stimulating hormone and beta-endorphin; and the glucocorticoids.
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The Human Glucocorticoid Receptor: Molecular Basis of Biologic Function
Nicolas C. Nicolaides,Zoi Galata,Tomoshige Kino,George P. Chrousos,George P. Chrousos,George P. Chrousos,Evangelia Charmandari,Evangelia Charmandari,Evangelia Charmandari +8 more
TL;DR: The characterization of the subfamily of steroid hormone receptors has enhanced understanding of how a set of hormonally derived lipophilic ligands controls cellular and molecular functions to influence development and help achieve homeostasis.
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Pediatric stress: hormonal mediators and human development.
TL;DR: The vulnerability of individuals to develop varying degrees and/or components of the above life-long syndrome is defined by as yet unidentified genetic factors, which account for up to 60% of the variance.
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Stress, the stress system and the role of glucocorticoids.
Nicolas C. Nicolaides,Elli Kyratzi,Agaristi Lamprokostopoulou,George P. Chrousos,Evangelia Charmandari +4 more
TL;DR: The central and peripheral components of thestress system are described, a comprehensive overview of the stress response is provided, and the role of glucocorticoids in a broad spectrum of stress-related diseases is discussed.
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Generalized Glucocorticoid Resistance: Clinical Aspects, Molecular Mechanisms, and Implications of a Rare Genetic Disorder
TL;DR: The study of functional defects of natural hGR mutants enhances the understanding of the molecular mechanisms of hGR action and highlights the importance of integrated cellular and molecular signaling mechanisms for maintaining homeostasis and preserving normal physiology.