F
Fabio Ferrarelli
Researcher at University of Pittsburgh
Publications - 127
Citations - 10119
Fabio Ferrarelli is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Sleep spindle & Non-rapid eye movement sleep. The author has an hindex of 40, co-authored 96 publications receiving 8405 citations. Previous affiliations of Fabio Ferrarelli include University of Milan & University of Wisconsin-Madison.
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Journal ArticleDOI
Breakdown of cortical effective connectivity during sleep.
Marcello Massimini,Fabio Ferrarelli,Fabio Ferrarelli,Reto Huber,Reto Huber,Steve K. Esser,Steve K. Esser,Harpreet Singh,Harpreet Singh,Giulio Tononi,Giulio Tononi +10 more
TL;DR: The fading of consciousness during certain stages of sleep may be related to a breakdown in cortical effective connectivity, as measured by transcranial magnetic stimulation and high-density electroencephalography.
Journal ArticleDOI
The sleep slow oscillation as a traveling wave.
TL;DR: It is shown here that each cycle of the slow oscillation is a traveling wave, which provides a blueprint of cortical excitability and connectivity and may play a role in spike timing-dependent synaptic plasticity during sleep.
Journal ArticleDOI
Arm immobilization causes cortical plastic changes and locally decreases sleep slow wave activity.
Reto Huber,M. Felice Ghilardi,Marcello Massimini,Fabio Ferrarelli,Brady A. Riedner,Michael J. Peterson,Giulio Tononi +6 more
TL;DR: If a subject's arm is immobilized during the day, motor performance deteriorates and both somatosensory and motor evoked potentials decrease over contralateral sensorimotor cortex, indicative of local synaptic depression, suggesting cortical plasticity is linked to local sleep regulation without learning in the classical sense.
Journal ArticleDOI
Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness
Fabio Ferrarelli,Marcello Massimini,Simone Sarasso,Adenauer G. Casali,Brady A. Riedner,Giuditta Angelini,Giulio Tononi,Robert A. Pearce +7 more
TL;DR: It is found that, unlike during wakefulness, wherein TMS triggered responses in multiple cortical areas lasting for >300 ms, during midazolam-induced LOC, TMS-evoked activity was local and of shorter duration, and a measure of the propagation of evoked cortical currents could reliably discriminate between consciousness and LOC.
Journal ArticleDOI
Triggering sleep slow waves by transcranial magnetic stimulation
Marcello Massimini,Fabio Ferrarelli,Steve K. Esser,Brady A. Riedner,Reto Huber,Michael Murphy,Michael J. Peterson,Giulio Tononi +7 more
TL;DR: TMS triggering of slow waves reveals intrinsic bistability in thalamocortical networks during non-rapid eye movement sleep and leads to a deepening of sleep and to an increase in EEG slow-wave activity, which is thought to play a role in brain restoration and memory consolidation.