F
Fábio Santos de Souza
Researcher at Federal University of Paraíba
Publications - 44
Citations - 461
Fábio Santos de Souza is an academic researcher from Federal University of Paraíba. The author has contributed to research in topics: Solubility & Chemistry. The author has an hindex of 11, co-authored 37 publications receiving 380 citations. Previous affiliations of Fábio Santos de Souza include Federal University of Pernambuco.
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Journal ArticleDOI
Anxiolytic-like activity and GC-MS analysis of (R)-(+)-limonene fragrance, a natural compound found in foods and plants.
Naiana G. P. B. Lima,Damião Pergentino de Sousa,Flávia Cristina Fernandes Pimenta,Mateus Feitosa Alves,Fábio Santos de Souza,Rui Oliveira Macêdo,Ricardo Barros Cardoso,Liana Clébia Soares Lima de Morais,Margareth de Fátima Formiga Melo Diniz,Reinaldo Nóbrega de Almeida +9 more
TL;DR: The data indicate that (+)-limonene could be used in aromatherapy as an antianxiety agent and suggest possible connections between the volatility of (+)- Limonene and its anxiolytic-like effect on the parameters evaluated in the elevated plus maze test.
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Thermal characterization of the solid state and raw material fluconazole by thermal analysis and pyrolysis coupled to GC/MS
Elisana Afonso de Moura,Lidiane Pinto Correia,Márcia Ferraz Pinto,José Valdilânio Virgulino Procópio,Fábio Santos de Souza,Rui Oliveira Macêdo,Rui Oliveira Macêdo +6 more
TL;DR: In this article, the thermal characterization of the raw material and different fluconazole crystals, obtained through recrystallization with different solvents using thermoanalytical techniques (TG, DTA, DSC-50 and DSC Photovisual, Dsc-60) and Pyr-GC/MS was studied.
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A Preformulation Study of a New Medicine for Chagas Disease Treatment: Physicochemical Characterization, Thermal Stability, and Compatibility of Benznidazole
José Lamartine Soares-Sobrinho,José Lamartine Soares-Sobrinho,Monica Felts de La Roca Soares,Monica Felts de La Roca Soares,Pablo Queiroz Lopes,Lidiane Pinto Correia,Fábio Santos de Souza,Rui Oliveira Macêdo,Pedro José Rolim-Neto +8 more
TL;DR: The compatibility study evidenced two possible chemical incompatibilities between BNZ and the tested excipients, both associated by the authors to the reaction of the BNZ's amine and a polymer carbohydrate’s carbonile, being maillard reactions.
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Studies of cimetidine pre-formulated and tablets for TG and DSC coupled to the photovisual system
TL;DR: In this article, the compatibility of pre-formulated drug-excipient mixtures and tablets of cimetidine by TG and DSC coupled to a photovisualization system was studied.
Journal ArticleDOI
Application of thermal analysis and pyrolysis coupled to GC/MS in the qualification of simvastatin pharmaceutical raw material
José Valdilânio Virgulino Procópio,José Valdilânio Virgulino Procópio,Valmir Gomes de Souza,Rodrigo Albuquerque da Costa,Lidiane Pinto Correia,Fábio Santos de Souza,Fábio Santos de Souza,Rui Oliveira Macêdo,Rui Oliveira Macêdo +8 more
TL;DR: In this article, the authors applied thermal characterization of simvastatin (SV) raw material using thermoanalytical techniques and its degradation products by Pyrolysis coupled to Gas chromatography/Mass spectrometry (Pyr-GC/MS).