F
Fabricia Petronilho
Researcher at Sewanee: The University of the South
Publications - 167
Citations - 3708
Fabricia Petronilho is an academic researcher from Sewanee: The University of the South. The author has contributed to research in topics: Oxidative stress & Sepsis. The author has an hindex of 31, co-authored 148 publications receiving 2771 citations. Previous affiliations of Fabricia Petronilho include Universidade do Extremo Sul Catarinense.
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Journal ArticleDOI
The NLRP3 Inflammasome and Its Role in Sepsis Development.
Lucineia Gainski Danielski,Amanda Della Giustina,Sandra Bonfante,Tatiana Barichello,Fabricia Petronilho +4 more
TL;DR: Evidence is elucidated to understand the connection between sepsis development and the NLRP3 inflammasome, the most widely investigated member of this class of receptor.
Journal ArticleDOI
Oxidative stress and mitochondrial dysfunction contributes to postoperative cognitive dysfunction in elderly rats.
Martins Back Netto,Aloir Neri de Oliveira Junior,Mariana Pereira de Souza Goldim,Khiany Mathias,Maria Eduarda Fileti,Naiana da Rosa,Ana Olívia Martins Laurentino,Bianca Xavier de Farias,Ana Beatriz Costa,Gislaine T. Rezin,Jucélia Jeremias Fortunato,Amanda Della Giustina,Tatiana Barichello,Felipe Dal-Pizzol,Fabricia Petronilho +14 more
TL;DR: Elderly rats submitted to an experimental model of tibial fracture displayed memory impairment accompanied by an increase in oxidative stress, mitochondrial dysfunction and reduced neurotrophin level.
Journal ArticleDOI
Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture
Omar J. Cassol-Jr,Clarissa M. Comim,Bruno Rosa Silva,Fernanda V. Hermani,Larissa Constantino,Francine Felisberto,Fabricia Petronilho,Jaime Eduardo Cecílio Hallak,Bruno Spinosa De Martinis,Antonio Waldo Zuardi,José Alexandre de Souza Crippa,João Quevedo,Felipe Dal-Pizzol +12 more
TL;DR: The data provide the first experimental demonstration that CBD reduces the consequences of sepsis induced by CLP in rats, by decreasing oxidative stress in peripheral organs and in the brain, improving impaired cognitive function, and decreasing mortality.
Journal ArticleDOI
Plasma nitric oxide, endothelin‐1, arginase and superoxide dismutase in pre‐eclamptic women
Fabiana Bernardi,Larissa Constantino,Roberta Albino Machado,Fabricia Petronilho,Felipe Dal-Pizzol +4 more
TL;DR: The aim of this study was to determine several parameters of nitric oxide metabolism in pre‐eclamptic patients and to establish a priori whether these parameters are related to EMT or not.
Journal ArticleDOI
Long-Term Cognitive Outcomes After Sepsis: a Translational Systematic Review.
Tatiana Barichello,Pavani Sayana,Vijayasree V. Giridharan,Anithachristy S. Arumanayagam,Boomadevi Narendran,Amanda Della Giustina,Amanda Della Giustina,Fabricia Petronilho,João Quevedo,Felipe Dal-Pizzol +9 more
TL;DR: Clinical studies have showed that sepsis survivors presented increased bodily symptoms such as fatigue, pain, visual disturbances, gastrointestinal problems, and neuropsychiatric problems compared to before sepsi, and the rodents presented long-term cognitive impairment in different behavioral tasks that were prevented by blocking the mechanism of action of these inflammatory mediators.