F
Fang Xie
Researcher at University of South Carolina
Publications - 8
Citations - 1005
Fang Xie is an academic researcher from University of South Carolina. The author has contributed to research in topics: Click chemistry & Cycloaddition. The author has an hindex of 5, co-authored 8 publications receiving 945 citations.
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Journal ArticleDOI
A fluorogenic 1,3-dipolar cycloaddition reaction of 3-azidocoumarins and acetylenes.
TL;DR: Copper(I)-catalyzed 1,3-dipolar cycloaddition reaction of nonfluorescent 3-azidocoumarins and terminal alkynes afforded intense fluorescent 1,2, 3-triazole products, which has potential in bioconjugation and bioimaging applications.
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Synthesis and anti-angiogenesis activity of coumarin derivatives
TL;DR: 7-diethylaminocoumarin molecules can be utilized as lead compounds to develop potential nontoxic angiogenesis inhibitors and small molecular ligands to target HUVEC.
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A fluorogenic ‘click’ reaction of azidoanthracene derivatives
TL;DR: A fluorogenic reaction using anthracene azides as starting materials produces a strongly fluorescent triazole product with high quantum yields and can be used in the synthesis and screening of fluorescent dyes combinatorially.
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Chemoselective derivatization of a bionanoparticle by click reaction and ATRP reaction
TL;DR: Horse spleen apoferritin, the hollow protein shell derived from ferritin can be chemoselectively modified at the lysine residues, which affords a robust scaffold for further chemical reactions including Cu(i)-catalyzed azide-alkyne cycloaddition reaction and atom transfer radical polymerization reaction.
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Synthesis and anti-Angiogenesis Activity of Coumarin Derivatives.
TL;DR: A series of 7-diethylaminocoumarin compounds were synthesized and the cytotoxicities were tested against human umbilical vein endothelial cell (HUVEC) and some cancer cells.