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Farah Idali

Researcher at Avicenna Research Institute

Publications -  23
Citations -  1210

Farah Idali is an academic researcher from Avicenna Research Institute. The author has contributed to research in topics: Immune system & Interleukin 21. The author has an hindex of 11, co-authored 21 publications receiving 1133 citations. Previous affiliations of Farah Idali include Karolinska Institutet & Karolinska University Hospital.

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The human antimicrobial and chemotactic peptides LL-37 and α-defensins are expressed by specific lymphocyte and monocyte populations

TL;DR: The findings suggest that microbicidal peptides are effector molecules of lymphocytes and that antibacterial activity previously shown to be derived from T and NK cells may be partly mediated by the antibacterial peptides LL-37 and HNP 1-3.
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Analysis of regulatory T cell associated forkhead box P3 expression in the lungs of patients with sarcoidosis.

TL;DR: There is a reduced expression of regulatory T cell associated genes in BALF CD4+ T cells in sarcoidosis, and the data suggest an effector function of AV2S3+ lung‐accumulated T Cells in sarCOidosis.
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Reduced Th1 response in the lungs of HLA-DRB1*0301 patients with pulmonary sarcoidosis

TL;DR: Patterns of cytokine expression in bronchoalveolar lavage cells and BAL fluid from patients with pulmonary sarcoidosis and controls show a reduced expression of T-helper cell type-1 cytokines in human leukocyte-associated antigen-DRB1*0301 positive patients, which may relate to their good prognosis.
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No evidence of altered alveolar macrophage polarization, but reduced expression of TLR2, in bronchoalveolar lavage cells in sarcoidosis

TL;DR: Overall, there was no evidence for alveolar macrophage polarization in sarcoidosis, but there was a reduced TLR2 mRNA expression in patients with Löfgren's syndrome, which may be of relevance for macrophages interactions with a postulated sarcoIDosis pathogen, and for the characteristics of the ensuing T cell response.