Objective:To evaluate the value of diffusion weighted imaging(DWI) and apparent diffusion coefficient(ADC) in the diagnosis of pancreatic carcinoma.Methods:35 patients with pancreatic carcinoma and 32 normal control subjects were collected.Diffusion weighted magnetic resonance imaging(DWI) was performed,the b value in DWI was:50s/mm2,400s/mm2,and 700s/mm2.The ADC value of the pancreatic carcinoma,the pancreatic tissue adjacent to the tumor and the normal control subject were measured respectively and analyzed.The largest diameter of the pancreatic cancer on T2WI,DWI(b value was 400s/mm2),and dynamic enhanced MRI were measured and analyzed.Results:Of the 3 groups with different b value,the ADC value of pancreatic carcinoma showed significant statistical differences compared with that of the non-cancerous tissue and normal control group,but the ADC value of the non-cancerous tissue and normal control group showed no significant difference.No statistical difference was existed in the biggest diameter of pancreatic cancer in T2WI、DWI and dynamic enhanced MRI.Conclusion:The pancreatic carcinoma can be clearly displayed on DWI,the DWI image quality was the best as b value = 400s/mm2.Analysis of DWI in combination with ADC value is helpful in the detection of pancreatic carcinoma foci.

Study of the Value of DWI in the Diagnosis of Pancreatic Carcinoma

The Performance Comparison of 18F-FDG PET/MRI and 18F-FDG PET/CT for the Identification of Pancreatic Neoplasms

OBJECTIVE This retrospective study aimed to evaluate the diagnostic efficiency of simultaneous positron emission tomography/magnetic resonance imaging (PET/MR) in differentiating the benign and malignant of pancreatic tumors as well as the differentiation of pancreatic cancer. METHODS A total of 62 patients with suspected pancreatic tumors, diagnosed by PET/MR examinations, were collected in this study. These patients were divided into benign group and malignant group. The characteristics of the morphological MR, apparent diffusion coefficient (ADC), the mean of standardized uptake value (SUVmean), maximum values of standardized uptake value (SUVmax), in lesions were measured, and the novel parameters SUVpeak/ADC and SUVmax/ADC were constructed. The diagnostic efficiency for differentiating the benign and malignant lesions was analyzed by receiver operating characteristic (ROC) curve, and the diagnosis efficiency for the differentiation of pancreatic cancer was analyzed by Spearman correlation analysis. RESULTS In differentiating the benign and malignant of pancreatic tumors, the diagnostic efficiency increased in the order of SUVpeak (AUROC: 0.760), SUVmax (AUROC: 0.774), T1T2 (AUROC: 0.789), ADC (AUROC: 0.817), SUVpeak/ADC (AUROC: 0.836), SUVmax/ADC (AUROC: 0.847). There was no significant correlation for SUVmax, SUVpeak, ADC, SUVpeak/ADC, and SUVmax/ADC with the differentiation of pancreatic cancer (P > 0.05). Besides, T1T2 was not significantly correlated to the differentiation of pancreatic cancer (P = 0.026, r = -0.406). CONCLUSION The integration of PET/MR imaging could be used to efficiently diagnose whether the pancreatic tumor was benign or malignant. The SUVmax/ADC was the most efficient metric, while it could not help in the differentiation of pancreatic cancer.

Feng Xiang

Papers

Positron emission tomography/magnetic resonance imaging for the diagnosis and differentiation of pancreatic tumors.