The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).

Cyclic AMP (adenosine 3',5'-monophosphate or cyclic adenylate) has now been established as a second messenger mediating many of the effects of a variety of hormones. Several of the metabolic effects mediated by cyclic AMP are discussed, and it is suggested that certain other ("functional" or "mechanical") hormonal effects may be similarly mediated. In particular, the evidence presented supports the hypothesis that the positive inotropic response to the catecholamines is mediated by cyclic AMP. Although knowledge of the biological role of cyclic AMP has not been widely applied clinically, sufficient knowledge has now accumulated to make research in this area desirable.

Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)

Adenosine 3',5'-monophosphate in biological materials. II. The measurement of adenosine 3',5'-monophosphate in tissues and the role of the cyclic nucleotide in the lipolytic response of fat to epinephrine.

Spat, Andras, and Laszlo Hunyady. Control of Aldosterone Secretion: A Model for Convergence in Cellular Signaling Pathways. Physiol Rev 84: 489–539, 2004; 10.1152/physrev.00030.2003.—Aldosterone se...

Control of Aldosterone Secretion: A Model for Convergence in Cellular Signaling Pathways

Adenyl cyclase. IV. The effects of neurohormones on the formation of adenosine 3',5'-phosphate by preparations from brain and other tissues.

http://www.jbc.org/content/234/6/1421.full.pdf

Fernand G. Péron

Papers

Influence of adenosine 3',5'-monophosphate on corticoid production by rat adrenal glands.