F
Focko F. G. Rommerts
Researcher at Erasmus University Rotterdam
Publications - 125
Citations - 4008
Focko F. G. Rommerts is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Leydig cell & Sertoli cell. The author has an hindex of 36, co-authored 125 publications receiving 3957 citations.
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Journal ArticleDOI
Exogenous lactate is essential for metabolic activities in isolated rat spermatocytes and spermatids.
TL;DR: It is concluded that isolated spermatocytes and round sper matids may utilize lactate, perhaps secreted by Sertoli cells, as the main source of energy.
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Sertoli–Leydig cell communication via an LHRH-like factor
TL;DR: It is demonstrated that seminiferous tubules from both the rat and the stumptailed macaque contain a factor which has LHRH-like receptor-binding and biological activity in vitro, but which is immunologically distinct from native LHRh.
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Regulation of survival of rat pachytene spermatocytes by lactate supply from Sertoli cells
Nicolet H. P. M. Jutte,R. Jansen,J. A. Grootegoed,Focko F. G. Rommerts,O. P. F. Clausen,H.J. van der Molen +5 more
TL;DR: It is concluded that the activity and survival of pachytene spermatocytes in vitro can be regulated by the supply of lactate from Sertoli cells.
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FSH stimulation of the production of pyruvate and lactate by rat Sertoli cells may be involved in hormonal regulation of spermatogenesis
TL;DR: It is suggested that pyruvate and lactate are major products from Sertoli cells which can support synthetic activities in germ cells, and the present results indicate thatpyruvates may play a role in the hormonal regulation of spermatogenesis.
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Rapid Androgen Actions on Calcium Signaling in Rat Sertoli Cells and Two Human Prostatic Cell Lines: Similar Biphasic Responses Between 1 Picomolar and 100 Nanomolar Concentrations
TL;DR: Androgen-induced calcium fluxes and gap junctional intercellular communication (GJIC) were studied in three different cell types to postulate the existence of an alternative cell surface receptor system with biphasic response characteristics (high and low affinity).