F
Fox David Nathan Abraham
Researcher at Pfizer
Publications - 29
Citations - 754
Fox David Nathan Abraham is an academic researcher from Pfizer. The author has contributed to research in topics: Borane & Agonist. The author has an hindex of 15, co-authored 29 publications receiving 735 citations.
Papers
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Journal ArticleDOI
Pharmacological Options in the Treatment of Benign Prostatic Hyperplasia
Journal ArticleDOI
Asymmetric Synthesis of Cyclic Ethers by Rearrangement of Oxonium Ylides Generated from Chiral Copper Carbenoids
J. Stephen Clark,Mark Fretwell,Gavin A. Whitlock,Christopher J. Burns,Fox David Nathan Abraham +4 more
TL;DR: In this article, a chiral copper carbenoid with the oxygen atom of a pendant allylic ether was obtained using a copper complex of the enantiomerically pure diimine 1a.
Journal ArticleDOI
Design of Second Generation Phosphodiesterase 5 Inhibitors
TL;DR: Key elements used in this programme are high throughput screening (HTS), exploitation of co-crystal structural information for bound inhibitor in the PDE5 active site, and employment of parallel chemistry to speed progress.
Patent
Quinoline and quinazoline compounds useful in therapy
TL;DR: The compounds of formula (I) as discussed by the authors are useful in the treatment of inter alia benign prostatic hyperplasia, where R1 represents C?1-4? alkoxy optionally substituted by one or more fluorine atoms.
Patent
5,7-diaminopyrazolo`4,3-d!pyrimidines useful in the treatment of hypertension
Andrew Simon Bell,David G. Brown,Fox David Nathan Abraham,Ian Roger Marsh,Morrell Andrew Ian,Michael John Palmer,Carol Ann Winslow +6 more
TL;DR: In this article, a pharmaceutical composition containing compounds of formula (I) and use thereof for manufacture of medicaments for treatment of hypertension is described. But the composition is not described.