F
Francesco Orio
Researcher at Parthenope University of Naples
Publications - 191
Citations - 10053
Francesco Orio is an academic researcher from Parthenope University of Naples. The author has contributed to research in topics: Polycystic ovary & Insulin resistance. The author has an hindex of 53, co-authored 191 publications receiving 9120 citations. Previous affiliations of Francesco Orio include University of Naples Federico II & University of Palermo.
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Journal ArticleDOI
Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review.
TL;DR: The uses of metformin are analyzed not only for the treatment of all PCOS-related disturbances such as menstrual disorders, anovulatory infertility, increased abortion, or complicated pregnancy risk, hyperandrogenism, endometrial, metabolic and cardiovascular abnormalities, but also for the prevention of the syndrome.
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Early impairment of endothelial structure and function in young normal-weight women with polycystic ovary syndrome.
Francesco Orio,Stefano Palomba,Teresa Cascella,Biagio De Simone,Sebastiano Di Biase,Tiziana Russo,Donato Labella,Fulvio Zullo,Gaetano Lombardi,Annamaria Colao +9 more
TL;DR: The data show that young, normal-weight, nondyslipidemic, nonhypertensive women with PCOS have an early impairment of endothelial structure and function.
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Abdominal fat quantity and distribution in women with polycystic ovary syndrome and extent of its relation to insulin resistance.
Enrico Carmina,S. Bucchieri,Antonella Esposito,Antonio Del Puente,Pasquale Mansueto,Francesco Orio,Gaetana Di Fede,Giovam Battista Rini +7 more
TL;DR: Most obese subjects, independent of being affected by PCOS, have an abdominal form of obesity, however, abdominal fat excess may not be the only determinant of insulin resistance in PCOS.
Journal ArticleDOI
The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study.
Francesco Orio,Stefano Palomba,Letizia Spinelli,Teresa Cascella,Libuse Tauchmanovà,Fulvio Zullo,Gaetano Lombardi,Annamaria Colao +7 more
TL;DR: The data show the detrimental effect of PCOS on the cardiovascular system even in young women asymptomatic for cardiac disease.
Journal ArticleDOI
Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as the first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome.
Stefano Palomba,Francesco Orio,Angela Falbo,Francesco Manguso,Tiziana Russo,Teresa Cascella,Achille Tolino,Enrico Carmina,Annamaria Colao,Fulvio Zullo +9 more
TL;DR: Six-month metformin administration is significantly more effective than six-cycle CC treatment in improving fertility in anovulatory nonobese PCOS women.