1980 Preface * 1999 Preface * 1999 Acknowledgements * Introduction * 1 Circular Logic * 2 Phase Singularities (Screwy Results of Circular Logic) * 3 The Rules of the Ring * 4 Ring Populations * 5 Getting Off the Ring * 6 Attracting Cycles and Isochrons * 7 Measuring the Trajectories of a Circadian Clock * 8 Populations of Attractor Cycle Oscillators * 9 Excitable Kinetics and Excitable Media * 10 The Varieties of Phaseless Experience: In Which the Geometrical Orderliness of Rhythmic Organization Breaks Down in Diverse Ways * 11 The Firefly Machine 12 Energy Metabolism in Cells * 13 The Malonic Acid Reagent ('Sodium Geometrate') * 14 Electrical Rhythmicity and Excitability in Cell Membranes * 15 The Aggregation of Slime Mold Amoebae * 16 Numerical Organizing Centers * 17 Electrical Singular Filaments in the Heart Wall * 18 Pattern Formation in the Fungi * 19 Circadian Rhythms in General * 20 The Circadian Clocks of Insect Eclosion * 21 The Flower of Kalanchoe * 22 The Cell Mitotic Cycle * 23 The Female Cycle * References * Index of Names * Index of Subjects

https://www.cambridge.org/core/services/aop-cambridge-core/content/view/596B270197FE27DE5FABB598B6210622/S0025557200150892a.pdf/div-class-title-span-class-italic-the-geometry-of-biological-time-span-by-a-t-winfree-pp-544-dm68-corrected-second-printing-1990-isbn-3-540-52528-9-springer-div.pdf

The geometry of biological time , by A. T. Winfree. Pp 544. DM68. Corrected Second Printing 1990. ISBN 3-540-52528-9 (Springer)

https://users.dimi.uniud.it/~antonio.dangelo/Robotica/2012/helper/leggedRobot/Ijspeert08NN.pdf

2008 Special Issue: Central pattern generators for locomotion control in animals and robots: A review

Skin plays an important role in mediating our interactions with the world. Recreating the properties of skin using electronic devices could have profound implications for prosthetics and medicine. The pursuit of artificial skin has inspired innovations in materials to imitate skin's unique characteristics, including mechanical durability and stretchability, biodegradability, and the ability to measure a diversity of complex sensations over large areas. New materials and fabrication strategies are being developed to make mechanically compliant and multifunctional skin-like electronics, and improve brain/machine interfaces that enable transmission of the skin's signals into the body. This Review will cover materials and devices designed for mimicking the skin's ability to sense and generate biomimetic signals.

Pursuing prosthetic electronic skin.

Hardware implementations of spiking neurons can be extremely useful for a large variety of applications, ranging from high-speed modeling of large-scale neural systems to real-time behaving systems, to bidirectional brain-machine interfaces. The specific circuit solutions used to implement silicon neurons depend on the application requirements. In this paper we describe the most common building blocks and techniques used to implement these circuits, and present an overview of a wide range of neuromorphic silicon neurons, which implement different computational models, ranging from biophysically realistic and conductance-based Hodgkin-Huxley models to bi-dimensional generalized adaptive integrate and fire models. We compare the different design methodologies used for each silicon neuron design described, and demonstrate their features with experimental results, measured from a wide range of fabricated VLSI chips.

/pdf/neuromorphic-silicon-neuron-circuits-3fphnmpvq9.pdf

Neuromorphic Silicon Neuron Circuits

Feature extraction is a significant method to extract the useful information which is hidden in surface electromyography (EMG) signal and to remove the unwanted part and interferences. To be successful in classification of the EMG signal, selection of a feature vector ought to be carefully considered. However, numerous studies of the EMG signal classification have used a feature set that have contained a number of redundant features. In this study, most complete and up-to-date thirty-seven time domain and frequency domain features have been proposed to be studied their properties. The results, which were verified by scatter plot of features, statistical analysis and classifier, indicated that most time domain features are superfluity and redundancy. They can be grouped according to mathematical property and information into four main types: energy and complexity, frequency, prediction model, and time-dependence. On the other hand, all frequency domain features are calculated based on statistical parameters of EMG power spectral density. Its performance in class separability viewpoint is not suitable for EMG recognition system. Recommendation of features to avoid the usage of redundant features for classifier in EMG signal classification applications is also proposed in this study.

Feature reduction and selection for EMG signal classification

Upper limb prostheses are increasingly resembling the limbs they seek to replace in both form and functionality, including the design and development of multifingered hands and wrists. Hence, it becomes necessary to control large numbers of degrees of freedom (DOFs), required for individuated finger movements, preferably using noninvasive signals. While existing control paradigms are typically used to drive a single-DOF hook-based configurations, dexterous tasks such as individual finger movements would require more elaborate control schemes. We show that it is possible to decode individual flexion and extension movements of each finger (ten movements) with greater than 90% accuracy in a transradial amputee using only noninvasive surface myoelectric signals. Further, comparison of decoding accuracy from a transradial amputee and able-bodied subjects shows no statistically significant difference ( p < 0.05) between these subjects. These results are encouraging for the development of real-time control strategies based on the surface myoelectric signal to control dexterous prosthetic hands.

Decoding of Individuated Finger Movements Using Surface Electromyography

Our ability to manipulate objects dexterously relies fundamentally on sensory signals originating from the hand. To restore motor function with upper-limb neuroprostheses requires that somatosensory feedback be provided to the tetraplegic patient or amputee. Given the complexity of state-of-the-art prosthetic limbs and, thus, the huge state space they can traverse, it is desirable to minimize the need for the patient to learn associations between events impinging on the limb and arbitrary sensations. Accordingly, we have developed approaches to intuitively convey sensory information that is critical for object manipulation—information about contact location, pressure, and timing—through intracortical microstimulation of primary somatosensory cortex. In experiments with nonhuman primates, we show that we can elicit percepts that are projected to a localized patch of skin and that track the pressure exerted on the skin. In a real-time application, we demonstrate that animals can perform a tactile discrimination task equally well whether mechanical stimuli are delivered to their native fingers or to a prosthetic one. Finally, we propose that the timing of contact events can be signaled through phasic intracortical microstimulation at the onset and offset of object contact that mimics the ubiquitous on and off responses observed in primary somatosensory cortex to complement slowly varying pressure-related feedback. We anticipate that the proposed biomimetic feedback will considerably increase the dexterity and embodiment of upper-limb neuroprostheses and will constitute an important step in restoring touch to individuals who have lost it.

https://www.pnas.org/content/pnas/110/45/18279.full.pdf

Restoring the sense of touch with a prosthetic hand through a brain interface.

The fast pace of development of upper-limb prostheses requires a paradigm shift in EMG-based controls. Traditional control schemes are only capable of providing 2 degrees of freedom, which is insufficient for dexterous control of individual fingers. We present a framework where myoelectric signals from natural hand and finger movements can be decoded with a high accuracy. 32 surface-EMG electrodes were placed on the forearm of an able-bodied subject while performing individual finger movements. Using time-domain feature extraction methods as inputs to a neural network classifier, we show that 12 individuated flexion and extension movements of the fingers can be decoded with an accuracy higher than 98%. To our knowledge, this is the first instance in which such movements have been successfully decoded using surface-EMG. These preliminary findings provide a framework that will allow the results to be extended to non-invasive control of the next generation of upper-limb prostheses for amputees.

Towards the Control of Individual Fingers of a Prosthetic Hand Using Surface EMG Signals

As development toward multi-fingered dexterous prosthetic hands continues, there is a growing need for more flexible and intuitive control schemes. Through the use of generalized electrode placement and well-established methods of pattern recognition, we have developed a basis for asynchronous decoding of finger positions. With the present method, correlations as large as 0.91 and mean overall decoding errors of ∼11% have been achieved with average decoding errors of between decoded and actual conformation of the metacarpophalangeal joints of individual fingers. It is hoped that these results will serve as a foundation from which to encourage further investigation into more intuitive methods of myoelectric control of powered upper limb prostheses.

Continuous decoding of finger position from surface EMG signals for the control of powered prostheses

A low-cost, consumer-grade, EEG-based individual authentication system is proposed in this work While EEG signals are recorded, the subject performs four mental imagery tasks consisting of a baseline measurement, referential limb movement, counting, and rotation for 150 seconds each The 150 seconds of data are divided into one second segments, from which features are obtained Three sets of features are extracted from each electrode: 6th order autoregressive (AR) coefficients, power spectral density, and total power in five frequency bands Two additional sets of features are extracted from interhemispheric data: interhemispheric power differences and interhemispheric linear complexity These feature sets are combined into a feature vector that is then used by a linear support vector machine (SVM) with cross validation for classification The goal was to minimize both false accept rates (FARs) and false reject rates (FRRs) Using voting rules across groups of ten segments, we were able to achieve 100% classification accuracy for each subject in each task Though more work must be done with a larger subject pool as well as across multiple sessions, these results show that low-cost EEG authentication systems may be viable

Francesco Tenore

Papers

Decoding of Individuated Finger Movements Using Surface Electromyography

Restoring the sense of touch with a prosthetic hand through a brain interface.

Towards the Control of Individual Fingers of a Prosthetic Hand Using Surface EMG Signals

Continuous decoding of finger position from surface EMG signals for the control of powered prostheses

Low-cost electroencephalogram (EEG) based authentication