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Francisca Echeverría
Researcher at University of Chile
Publications - 22
Citations - 1149
Francisca Echeverría is an academic researcher from University of Chile. The author has contributed to research in topics: Polyunsaturated fatty acid & Docosahexaenoic acid. The author has an hindex of 14, co-authored 19 publications receiving 811 citations.
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Journal ArticleDOI
Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging
TL;DR: The aim of this review was to assess the role of FAs as PPARs ligands, in terms of their main functions associated with FA metabolism and their relevance in the prevention and treatment of related pathologies during human life span.
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Docosahexaenoic acid (DHA), a fundamental fatty acid for the brain: New dietary sources.
TL;DR: The importance of DHA in the human brain given its relevance in the development of the tissue and as neuroprotective agent is discussed and a critical view about the ways to supply this noble fatty acid to the population is included.
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Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-α and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation
María Catalina Hernandez-Rodas,Rodrigo Valenzuela,Francisca Echeverría,Miguel Ángel Rincón-Cervera,Alejandra Espinosa,Paola Illesca,Patricio Moya Muñoz,Alicia Corbari,Nalda Romero,Daniel González-Mañán,Luis A. Videla +10 more
TL;DR: DHA + EVOO supplementation significantly reduces hepatic steatosis, oxidative stress, systemic inflammation, and insulin resistance and is associated with the activation/inactivation of key transcription factors involved in the above-mentioned processes.
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Molecular adaptations underlying the beneficial effects of hydroxytyrosol in the pathogenic alterations induced by a high-fat diet in mouse liver: PPAR-α and Nrf2 activation, and NF-κB down-regulation
Rodrigo Valenzuela,Paola Illesca,Francisca Echeverría,Alejandra Espinosa,Miguel Ángel Rincón-Cervera,Macarena Ortiz,María Catalina Hernandez-Rodas,Alfonso Valenzuela,Luis A. Videla +8 more
TL;DR: Hydroxytyrosol (HT), a polyphenol with cytoprotective effects present in extra virgin olive oil, improves the cellular antioxidant capacity for activation of transcription factor Nrf2 and may reduce the liver alterations induced in high-fat diet (HFD)-fed mice.
Journal ArticleDOI
Hydroxytyrosol and Cytoprotection: A Projection for Clinical Interventions
TL;DR: The aim of this review was to assess the main properties of HT for human health with emphasis on those related to the possible prevention and/or treatment of non-communicable diseases.