F
Francisco C Figueiredo
Researcher at Royal Victoria Infirmary
Publications - 103
Citations - 3867
Francisco C Figueiredo is an academic researcher from Royal Victoria Infirmary. The author has contributed to research in topics: Transplantation & Stem cell. The author has an hindex of 29, co-authored 96 publications receiving 3105 citations. Previous affiliations of Francisco C Figueiredo include Newcastle upon Tyne Hospitals NHS Foundation Trust & University of Newcastle.
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Journal ArticleDOI
Amniotic membrane transplantation for acute chemical or thermal burns.
Daniel Meller,Renato T. F. Pires,Robert J.S Mack,Francisco C Figueiredo,Arnd Heiligenhaus,Woo Chan Park,Pinnita Prabhasawat,Thomas John,Stephen D. McLeod,Klaus P. Steuhl,Scheffer C.G. Tseng,Scheffer C.G. Tseng +11 more
TL;DR: Amniotic membrane transplantation is effective in promoting re-epithelialization and reducing inflammation, thus preventing scarring sequelae in the late stage and underscore the importance of immediate intervention in the acute stage of eyes with severely damaged ocular surface.
Journal ArticleDOI
Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications
Benjamin Sullivan,Leslie Crews,Elisabeth M. Messmer,Gary N. Foulks,Kelly K. Nichols,Philipp B. Baenninger,Gerd Geerling,Francisco C Figueiredo,Michael A. Lemp,Michael A. Lemp +9 more
TL;DR: Evaluation of the relationship between signs and symptoms of dry eye disease in a clinic‐based population and its impact on quality of life in a hospital-based population is conducted.
Journal ArticleDOI
13 years of cultured limbal epithelial cell therapy: a review of the outcomes
Oliver Baylis,Francisco C Figueiredo,Francisco C Figueiredo,Christin Henein,Majlinda Lako,Sajjad Ahmad,Sajjad Ahmad +6 more
TL;DR: The outcomes of this procedure over the past 13 years are reviewed with the aim of highlighting the best culture and surgical techniques to date.
Journal ArticleDOI
Differentiation of Human Embryonic Stem Cells into Corneal Epithelial‐Like Cells by In Vitro Replication of the Corneal Epithelial Stem Cell Niche
Sajjad Ahmad,Rebecca Stewart,Sun Yung,Sai Kolli,Sai Kolli,Lyle Armstrong,Miodrag Stojkovic,Francisco C Figueiredo,Francisco C Figueiredo,Majlinda Lako +9 more
TL;DR: It is shown that culturing of hESC on collagen IV using medium conditioned by the limbal fibroblasts results in the loss of pluripotency and differentiation into epithelial‐like cells, whichresults in the formation of terminally differentiated epithelial-like cells not only of the cornea but also of skin.
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Phase II Randomized, Double-Masked, Vehicle-Controlled Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis.
Stefano Bonini,Alessandro Lambiase,Paolo Rama,Francesco Sinigaglia,Marcello Allegretti,Wendy Chao,Flavio Mantelli,Elisabeth M. Messmer,Pasquale Aragona,Gerd Geerling,Leonardo Mastropasqua,Rita Mencucci,John K G Dart,Andrea Leonardi,Jesús Montero,Maurizio Rolando,Thomas Reinhard,Claus Cursiefen,Jaime Etxebarria,Eric E. Gabison,Jacek P. Szaflik,Nacim Bouheraoua,Maria De La Paz,Maite Sainz de la Maza,Edward Wylegala,Francisco C Figueiredo,Paolo Fogagnolo,Parwez Hossain,Katrin Lorenz,Pierre-Yves Robert,Jose M. Benitez del Castillo,Catherine Creuzot-Garcher,Friedrich E. Kruse,François Malecaze,Jesus Merayo-Lloves,Saaeha Rauz,Jorge L. Alió,Fiona Carley,Ramaesh Kanna,Carina Koppen,János Németh,Joaquim Murta,Luis Torrao +42 more
TL;DR: Topical rhNGF is safe and more effective than vehicle in promoting healing of moderate-to-severe NK, a rare degenerative corneal disease resulting from impairedCorneal innervation.