Francisco Girón-Rodríguez

TL;DR: Evidence is affords for the fact that selective BChE inhibitors should be further investigated as promising candidate molecules for AD therapy.

TL;DR: The objective of this work was to obtain casein hydrolysates with aspartic proteinases present in extracts from the artichoke flower and evaluate their antioxidant, antimicrobial, and angiotensin-I converting enzyme (ACE) inhibitory activity in vitro.

TL;DR: An attempt to address the problem of genotoxicity by using the TOPological Substructural MOlecular Design (TOPS-MODE) approach to develop and validate improved QSAR models for predicting the mutagenicity of a range of halogenated derivatives, demonstrating high predictivity with relevant mechanistic interpretation.

TL;DR: The results of this comparison showed that using fuzzy minimal for big and structurally diverse data sets gave an applicability domain similar to KMS and a better predictability models than both methods, K MS and MTSD.

TL;DR: From the peptide sequences identified in the hydrolysates, four peptides were detected that were already in their bioactive form (IAAEVYEHTEGSTTSY, HLFGPPGKKDPV, PIAAEvYEHTegSTTSy, and YAEERYPIL) and are reported to display antioxidant and ACE inhibitory activity.