Frederic H. Fahey

TL;DR: In lipoatrophic A-ZIP/F1 ‘fatless’ mice, and in mice treated with the peroxisome proliferator-activated receptor-γ inhibitor bisphenol A diglycidyl ether, marrow engraftment after irradiation is accelerated relative to wild-type or untreated mice, suggesting that antagonizing marrow adipogenesis may enhance haematopoietic recovery in clinical bone-marrow transplantation.

TL;DR: The favorable imaging performance and the clinical utility of 18F-fluoride PET, compared with 99mTc-diphosphonate scintigraphy, support the reconsideration of 18f- fluoride as a routine bone-imaging agent.

TL;DR: This model reproduces many of the defining features of human osteosarcoma including cytogenetic complexity and comparable gene expression signatures, histology, and metastatic behavior and provides a valuable platform for addressing the molecular genetics of osteosARcoma and for developing novel therapeutic strategies.

TL;DR: Results indicate that Hv1-dependent ROS production is responsible for a substantial fraction of brain damage at early time points after ischemic stroke and provide a rationale for Hv 1 as a therapeutic target for the treatment of isChemic stroke.

TL;DR: Hemodynamic and CBF (via positron emission tomography) measurements were determined at each experimental time point and dexmedetomidine decreased both cardiac output and heart rate during and 30 min after drug administration.