F
Frigga Roggel
Researcher at Ludwig Maximilian University of Munich
Publications - 3
Citations - 900
Frigga Roggel is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Permeability (electromagnetism) & Mitochondrial permeability transition pore. The author has an hindex of 3, co-authored 3 publications receiving 812 citations.
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Role of Kupffer cells in host defense and liver disease.
TL;DR: Kupffer cells constitute 80–90% of the tissue macrophages present in the body, and are therefore constantly exposed to gut‐derived bacteria, microbial debris and bacterial endotoxins, known to activate macrophage.
Journal ArticleDOI
Kupffer cell activation in normal and fibrotic livers increases portal pressure via thromboxane A2
Christian J. Steib,Alexander L. Gerbes,M. Bystron,Mark op den Winkel,Josef M. Härtl,Frigga Roggel,Thomas Prüfer,Burkhard Göke,Manfred Bilzer +8 more
TL;DR: KC activated by beta-glucans increase portal pressure through the release of TxA(2) as pivotal vasoconstrictor released by activated KC and is augmented in BDL induced fibrosis.
Journal ArticleDOI
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition.
Hans Zischka,Nathanael Larochette,Florian Hoffmann,Daniela Hamöller,Nora Jägemann,Josef Lichtmannegger,Luise Jennen,Josef Müller-Höcker,Frigga Roggel,Martin Göttlicher,Angelika M. Vollmar,Guido Kroemer +11 more
TL;DR: It is shown that the relative abundance of each population depends on the dose of the permeability transition inducer and the duration of the treatment time, and the impairment of mitochondria that were isolated from livers subjected to ischemia/reperfusion damage.