F
Furaha Florence Asani
Researcher at University of Johannesburg
Publications - 3
Citations - 230
Furaha Florence Asani is an academic researcher from University of Johannesburg. The author has contributed to research in topics: Calcitriol receptor & Gene. The author has an hindex of 3, co-authored 3 publications receiving 192 citations.
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Journal ArticleDOI
Regulation of the vitamin D receptor gene by environment, genetics and epigenetics.
TL;DR: The complex interaction and contributions of the three levels of VDR gene regulation are illuminated to endorse consideration of all three regulatory factors when studying gene regulation.
Journal ArticleDOI
Vitamin D Receptor Gene Expression and Function in a South African Population: Ethnicity, Vitamin D and FokI.
Vanessa O′Neill,Furaha Florence Asani,Tamsyn Jacki Jeffery,Donovan Sean Saccone,Liza Bornman +4 more
TL;DR: In this article, the T(f) allele of the functional SNP FokI, in exon 2 of VDR, results in a longer vitamin D receptor protein (VDR) isoform, proposed to be less active.
Journal ArticleDOI
Methylation of the Vitamin D Receptor (VDR) Gene, Together with Genetic Variation, Race, and Environment Influence the Signaling Efficacy of the Toll-Like Receptor 2/1-VDR Pathway.
Vanessa J. Meyer,Donovan Sean Saccone,Fidele Tugizimana,Furaha Florence Asani,Tamsyn Jacki Jeffery,Liza Bornman +5 more
TL;DR: regulation of VDR-mediated TLR2/1 signaling is multifactorial, involving interaction between environment [UVI and consequent 25(OH)D3 status], epigenetics (VDR methylation at key regulatory sites), and genetics (TLR1, TIRAP, and VDR SNPs).