G
G Alber
Researcher at Basel Institute for Immunology
Publications - 1
Citations - 2130
G Alber is an academic researcher from Basel Institute for Immunology. The author has contributed to research in topics: Antigen & Interleukin 12. The author has an hindex of 1, co-authored 1 publications receiving 2092 citations.
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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
TL;DR: It is found that ligation of CD40 by CD40L triggers the production of extremely high levels of bioactive IL-12, which is the most potent stimulus in upregulating the expression of ICAM-1, CD80, and CD86 molecules on DCs.